| Gene Symbol |
MVB12B
|
| Entrez Gene |
89853
|
| Alt Symbol |
C9orf28, FAM125B
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
multivesicular body subunit 12B
|
| Other Description |
ESCRT-I complex subunit MVB12B|family with sequence similarity 125, member B
|
| Swissprots |
Q9H7P6 Q8N6S7
|
| Accessions |
EAW87639 EAW87640 Q9H7P6 AJ420437 AK000001 BAA92226 AK024432 BAB15722 AK024441 BAB15731 AK293740 BAH11585 AK298023 BAH12706 AK307473 BC000122 BC028675 AAH28675 BC036326 BC041601 CK300748 DA339911 HQ448103 ADQ32584 XM_005252297 XP_005252354 XM_011519175 XP_011517477 XM_011519176 XP_011517478 XM_011519177 XP_011517479 XM_011519178 XP_011517480 XR_929872 NM_001011703 NP_001011703 NM_033446 NP_258257
|
| Function |
Component of the ESCRT-I complex, a regulator of vesicular trafficking process. Required for the sorting of endocytic ubiquitinated cargos into multivesicular bodies.
|
| Subcellular Location |
Endosome {ECO:0000305}. Late endosome membrane {ECO:0000305}; Peripheral membrane protein {ECO:0000305}.
|
| Top Pathways |
Endocytosis
|