Gene Symbol | MVB12B |
---|---|
Entrez Gene | 89853 |
Alt Symbol | C9orf28, FAM125B |
Species | Human |
Gene Type | protein-coding |
Description | multivesicular body subunit 12B |
Other Description | ESCRT-I complex subunit MVB12B|family with sequence similarity 125, member B |
Swissprots | Q9H7P6 Q8N6S7 |
Accessions | EAW87639 EAW87640 Q9H7P6 AJ420437 AK000001 BAA92226 AK024432 BAB15722 AK024441 BAB15731 AK293740 BAH11585 AK298023 BAH12706 AK307473 BC000122 BC028675 AAH28675 BC036326 BC041601 CK300748 DA339911 HQ448103 ADQ32584 XM_005252297 XP_005252354 XM_011519175 XP_011517477 XM_011519176 XP_011517478 XM_011519177 XP_011517479 XM_011519178 XP_011517480 XR_929872 NM_001011703 NP_001011703 NM_033446 NP_258257 |
Function | Component of the ESCRT-I complex, a regulator of vesicular trafficking process. Required for the sorting of endocytic ubiquitinated cargos into multivesicular bodies. |
Subcellular Location | Endosome {ECO:0000305}. Late endosome membrane {ECO:0000305}; Peripheral membrane protein {ECO:0000305}. |
Top Pathways | Endocytosis |
FMVB12B CRISPR/Cas9 KO Plasmid (h) - sc-413803 from Santa Cruz Biotechnology
|
||||||||
FMVB12B HDR Plasmid (h) - sc-413803-HDR from Santa Cruz Biotechnology
|
||||||||
FMVB12B Double Nickase Plasmid (h) - sc-413803-NIC from Santa Cruz Biotechnology
|
||||||||
FMVB12B Double Nickase Plasmid (h2) - sc-413803-NIC-2 from Santa Cruz Biotechnology
|
||||||||
FMVB12B CRISPR Activation Plasmid (h) - sc-413803-ACT from Santa Cruz Biotechnology
|
||||||||
FMVB12B CRISPR Activation Plasmid (h2) - sc-413803-ACT-2 from Santa Cruz Biotechnology
|
||||||||
FMVB12B Lentiviral Activation Particles (h) - sc-413803-LAC from Santa Cruz Biotechnology
|
||||||||
FMVB12B Lentiviral Activation Particles (h2) - sc-413803-LAC-2 from Santa Cruz Biotechnology
|
||||||||
MVB12B siRNA (h) - sc-92966 from Santa Cruz Biotechnology
|
||||||||
MVB12B shRNA Plasmid (h) - sc-92966-SH from Santa Cruz Biotechnology
|
||||||||
MVB12B shRNA (h) Lentiviral Particles - sc-92966-V from Santa Cruz Biotechnology
|
||||||||
MISSION® esiRNA - EHU061781 from Sigma-Aldrich
|
||||||||
CompoZr® Knockout ZFN Kit - CKOZFN8155 from Sigma-Aldrich
|
||||||||
CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND8155 from Sigma-Aldrich
|
||||||||
MVB12B siRNA (Human) - CRJ3869 from Cohesion Biosciences
|
||||||||
shRNA set against Human FAM125B (NM_033446.2) - SHH289433 from Creative biogene
|
||||||||
MVB12B shRNA Plasmid (Human) - CHJ3869 from Cohesion Biosciences
|