| Gene Symbol |
TECTA
|
| Entrez Gene |
7007
|
| Alt Symbol |
DFNA12, DFNA8, DFNB21
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
tectorin alpha
|
| Other Description |
alpha-tectorin
|
| Swissprots |
O75443
|
| Accessions |
AAC26019 CCQ43320 EAW67516 EAW67517 EAW67518 O75443 AF143331 BC156465 AAI56466 BC172509 AAI72509 NM_005422 NP_005413
|
| Function |
One of the major non-collagenous components of the tectorial membrane (By similarity). The tectorial membrane is an extracellular matrix of the inner ear that covers the neuroepithelium of the cochlea and contacts the stereocilia bundles of specialized sensory hair cells. Sound induces movement of these hair cells relative to the tectorial membrane, deflects the stereocilia and leads to fluctuations in hair-cell membrane potential, transducing sound into electrical signals. {ECO:0000250}.
|
| Subcellular Location |
Cell membrane {ECO:0000305}; Lipid-anchor, GPI-anchor {ECO:0000305}; Extracellular side {ECO:0000305}. Secreted, extracellular space, extracellular matrix. Note=Found in the non-collagenous matrix of the tectorial membrane. {ECO:0000250}.
|