| Gene Symbol |
TRNAU1AP
|
| Entrez Gene |
54952
|
| Alt Symbol |
PRO1902, SECP43, TRSPAP1
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
tRNA selenocysteine 1 associated protein 1
|
| Other Description |
tRNA selenocysteine 1-associated protein 1|tRNA selenocysteine associated protein (SECP43)|tRNA selenocysteine associated protein 1|tRNA selenocysteine-associated protein 1
|
| Swissprots |
Q86SU7 Q9NX07
|
| Accessions |
EAX07687 EAX07688 EAX07689 Q9NX07 AF118082 AAF22026 AK000510 BAA91217 AK023555 AK300162 BAH13226 AK309481 BC000680 AAH00680 BC035855 BC039879 AAH39879 BI602122 BQ014404 NM_017846 NP_060316 NR_003109
|
| Function |
Involved in the early steps of selenocysteine biosynthesis and tRNA(Sec) charging to the later steps resulting in the cotranslational incorporation of selenocysteine into selenoproteins. Stabilizes the SECISBP2, EEFSEC and tRNA(Sec) complex. May be involved in the methylation of tRNA(Sec). Enhances efficiency of selenoproteins synthesis (By similarity). {ECO:0000250}.
|
| Subcellular Location |
Nucleus {ECO:0000250}. Cytoplasm {ECO:0000250}. Note=Abundant in the nucleus. {ECO:0000250}.
|
![Western Blot: TRSPAP1 Overexpression Lysate (Adult Normal) [NBL1-17346] Left-Empty vector transfected control cell lysate (HEK293 cell lysate); Right -Over-expression Lysate for TRSPAP1.](http://www.bioprodhub.com/system/product_images/cel_products/5/sub_1/12139_TRSPAP1%2520Overexpression%2520Lysate%2520%2528Adult%2520Normal%2529-Western%2520Blot-NBL1-17346-img0002.jpg)