Gene Symbol | TRNAU1AP |
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Entrez Gene | 54952 |
Alt Symbol | PRO1902, SECP43, TRSPAP1 |
Species | Human |
Gene Type | protein-coding |
Description | tRNA selenocysteine 1 associated protein 1 |
Other Description | tRNA selenocysteine 1-associated protein 1|tRNA selenocysteine associated protein (SECP43)|tRNA selenocysteine associated protein 1|tRNA selenocysteine-associated protein 1 |
Swissprots | Q86SU7 Q9NX07 |
Accessions | EAX07687 EAX07688 EAX07689 Q9NX07 AF118082 AAF22026 AK000510 BAA91217 AK023555 AK300162 BAH13226 AK309481 BC000680 AAH00680 BC035855 BC039879 AAH39879 BI602122 BQ014404 NM_017846 NP_060316 NR_003109 |
Function | Involved in the early steps of selenocysteine biosynthesis and tRNA(Sec) charging to the later steps resulting in the cotranslational incorporation of selenocysteine into selenoproteins. Stabilizes the SECISBP2, EEFSEC and tRNA(Sec) complex. May be involved in the methylation of tRNA(Sec). Enhances efficiency of selenoproteins synthesis (By similarity). {ECO:0000250}. |
Subcellular Location | Nucleus {ECO:0000250}. Cytoplasm {ECO:0000250}. Note=Abundant in the nucleus. {ECO:0000250}. |
SECp43 CRISPR/Cas9 KO Plasmid (h) - sc-406265 from Santa Cruz Biotechnology
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SECp43 HDR Plasmid (h) - sc-406265-HDR from Santa Cruz Biotechnology
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SECp43 Double Nickase Plasmid (h) - sc-406265-NIC from Santa Cruz Biotechnology
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SECp43 Double Nickase Plasmid (h2) - sc-406265-NIC-2 from Santa Cruz Biotechnology
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SECp43 CRISPR Activation Plasmid (h) - sc-406265-ACT from Santa Cruz Biotechnology
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SECp43 CRISPR Activation Plasmid (h2) - sc-406265-ACT-2 from Santa Cruz Biotechnology
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SECp43 Lentiviral Activation Particles (h) - sc-406265-LAC from Santa Cruz Biotechnology
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SECp43 Lentiviral Activation Particles (h2) - sc-406265-LAC-2 from Santa Cruz Biotechnology
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SECp43 siRNA (h) - sc-88771 from Santa Cruz Biotechnology
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SECp43 shRNA Plasmid (h) - sc-88771-SH from Santa Cruz Biotechnology
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SECp43 shRNA (h) Lentiviral Particles - sc-88771-V from Santa Cruz Biotechnology
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MISSION® esiRNA - EHU155321 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN22045 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND22045 from Sigma-Aldrich
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MISSION® 3′UTR Lenti GoClone™ - HUTR06848 from Sigma-Aldrich
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TRNAU1AP siRNA (Human) - CRJ0352 from Cohesion Biosciences
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TRSPAP1 RNAi - H00054952-R01 from Novus Biologicals
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TRNAU1AP - MBS8220091 from MyBioSource
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shRNA set against Human TRNAU1 (NM_017846.4) - SHH435388 from Creative biogene
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shRNA set against Human TRSPAP1(NM_017846.4) - SHR212376 from Creative biogene
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Human TRNAU1AP siRNA - orb270853 from Biorbyt
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TRNAU1AP shRNA Plasmid (Human) - CHJ0352 from Cohesion Biosciences
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TRNAU1AP miRNA 3'UTR clone - MiUTR1H-10796 from Creative biogene
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