H1foo

Gene Symbol H1foo
Entrez Gene 171506
Alt Symbol C86609, H1.8, H1fo, H1oo
Species Mouse
Gene Type protein-coding
Description H1 histone family, member O, oocyte-specific
Other Description histone H1oo|oocyte-specific histone H1|oocyte-specific linker histone H1
Swissprots Q8VIK3
Accessions EDK99547 Q8VIK3 AK135944 BAE22736 AK162137 BAE36747 AK162154 AK165127 AY007195 AAG01890 BC137916 AAI37917 BC145046 XM_006505678 XP_006505741 NM_138311 NP_612184
Function May play a key role in the control of gene expression during oogenesis and early embryogenesis, presumably through the perturbation of chromatin structure. Essential for meiotic maturation of germinal vesicle-stage oocytes. The somatic type linker histone H1c is rapidly replaced by H1oo in a donor nucleus transplanted into an oocyte. The greater mobility of H1oo as compared to H1c may contribute to this rapid replacement and increased instability of the embryonic chromatin structure. The rapid replacement of H1c with H1oo may play an important role in nuclear remodeling. {ECO:0000269|PubMed:11171391, ECO:0000269|PubMed:14729479, ECO:0000269|PubMed:15371275, ECO:0000269|PubMed:17519519}.
Subcellular Location Cytoplasm {ECO:0000250}. Nucleus. Chromosome. Note=In the germinal vesicle oocyte, localizes to the condensed chromosomes. In the 1-cell embryo found in condensed maternal metaphase chromatin but not in the sperm head. Following second polar body extrusion, detected in the swollen sperm head as well as in the second polar body. Reduced expression in the nucleus in 2-cell embryo is seen as compared to 1-cell embryo.
Tissue Specificity Oocyte-specific. {ECO:0000269|PubMed:11171391, ECO:0000269|PubMed:15371275}.

H1FOO CRISPR/Cas9 KO Plasmid (m) - sc-431372 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Mouse

H1FOO HDR Plasmid (m) - sc-431372-HDR from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Mouse

H1FOO Double Nickase Plasmid (m) - sc-431372-NIC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Mouse

H1FOO Double Nickase Plasmid (m2) - sc-431372-NIC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Mouse

H1FOO CRISPR Activation Plasmid (m) - sc-431372-ACT from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Mouse

H1FOO CRISPR Activation Plasmid (m2) - sc-431372-ACT-2 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Mouse

H1FOO Lentiviral Activation Particles (m) - sc-431372-LAC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Mouse

H1FOO Lentiviral Activation Particles (m2) - sc-431372-LAC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Mouse

H1FOO siRNA (m) - sc-145847 from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Mouse

H1FOO shRNA Plasmid (m) - sc-145847-SH from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Mouse

H1FOO shRNA (m) Lentiviral Particles - sc-145847-V from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Mouse

CompoZr® Knockout ZFN Kit - CKOZFN33006 from Sigma-Aldrich

Category ZFN Kit
Prices $4,999.00
Sizes 1 kt

CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND33006 from Sigma-Aldrich

Category ZFN Kit
Prices $3,999.00
Sizes 1 kt

H1FOO siRNA (Mouse) - CRN1418 from Cohesion Biosciences

Category siRNA
Prices $340.00, $510.00
Sizes 15 nmol, 30 nmol
Species Reactivities Mouse

H1FOO - MBS8220937 from MyBioSource

Prices $365.00, $515.00
Sizes 15 nmol, 30 nmol
Species Reactivities Mouse

shRNA set against Mouse H1FOO (NM_138311.2) - SHH309766 from Creative biogene

Category siRNA
Species Reactivities Mouse

shRNA set against Mouse H1foo(NM_138311.2) - SHH111917 from Creative biogene

Category siRNA
Species Reactivities Mouse

Mouse H1FOO siRNA - orb290893 from Biorbyt

Category siRNA
Prices $485.00, $629.00
Sizes 15 nmol, 30 nmol
Species Reactivities Mouse

H1FOO shRNA Plasmid (Mouse) - CHN1418 from Cohesion Biosciences

Category siRNA
Prices $500.00, $750.00
Sizes 150 µg, 300 µg
Species Reactivities Mouse

H1FOO miRNA 3'UTR clone - MiUTR1M-05493 from Creative biogene

Species Reactivities Mouse
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