| Gene Symbol |
ZNF580
|
| Entrez Gene |
51157
|
| Alt Symbol |
-
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
zinc finger protein 580
|
| Other Description |
LDL induced EC protein|LDL-induced EC protein
|
| Swissprots |
B2RC05 Q9UK33 Q9NPP7
|
| Accessions |
EAW72399 Q9UK33 AF184939 AAD56549 AK123294 AK314888 BAG37402 AL359054 CAB94389 BC017698 AAH17698 BM700178 BM710177 BM793208 BQ477323 BU179609 HQ447203 ADQ31690 XM_005258967 XP_005259024 XM_006723236 XP_006723299 XM_011508867 XP_011507169 XM_011527018 XP_011525320 XM_011527019 XP_011525321 XM_011527020 XP_011525322 XM_011527021 XP_011525323 XM_011527022 XP_011525324 NM_001163423 NP_001156895 NM_016202 NP_057286 NM_207115 NP_996998
|
| Function |
Involved in the regulation of endothelial cell proliferation and migration. Mediates H(2)O(2)-induced leukocyte chemotaxis by elevating interleukin-8 production and may play a role in inflammation. May be involved in transcriptional regulation. {ECO:0000269|PubMed:20382120, ECO:0000269|PubMed:21830064}.
|
| Subcellular Location |
Nucleus {ECO:0000269|PubMed:20382120, ECO:0000269|PubMed:21599657}. Note=Colocalized with SMAD2 in the nucleus.
|
| Tissue Specificity |
Expressed in endothelial cells. {ECO:0000269|PubMed:21599657}.
|