Gene Symbol | ZNF580 |
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Entrez Gene | 51157 |
Alt Symbol | - |
Species | Human |
Gene Type | protein-coding |
Description | zinc finger protein 580 |
Other Description | LDL induced EC protein|LDL-induced EC protein |
Swissprots | B2RC05 Q9UK33 Q9NPP7 |
Accessions | EAW72399 Q9UK33 AF184939 AAD56549 AK123294 AK314888 BAG37402 AL359054 CAB94389 BC017698 AAH17698 BM700178 BM710177 BM793208 BQ477323 BU179609 HQ447203 ADQ31690 XM_005258967 XP_005259024 XM_006723236 XP_006723299 XM_011508867 XP_011507169 XM_011527018 XP_011525320 XM_011527019 XP_011525321 XM_011527020 XP_011525322 XM_011527021 XP_011525323 XM_011527022 XP_011525324 NM_001163423 NP_001156895 NM_016202 NP_057286 NM_207115 NP_996998 |
Function | Involved in the regulation of endothelial cell proliferation and migration. Mediates H(2)O(2)-induced leukocyte chemotaxis by elevating interleukin-8 production and may play a role in inflammation. May be involved in transcriptional regulation. {ECO:0000269|PubMed:20382120, ECO:0000269|PubMed:21830064}. |
Subcellular Location | Nucleus {ECO:0000269|PubMed:20382120, ECO:0000269|PubMed:21599657}. Note=Colocalized with SMAD2 in the nucleus. |
Tissue Specificity | Expressed in endothelial cells. {ECO:0000269|PubMed:21599657}. |
ZNF580 CRISPR/Cas9 KO Plasmid (h) - sc-406194 from Santa Cruz Biotechnology
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ZNF580 HDR Plasmid (h) - sc-406194-HDR from Santa Cruz Biotechnology
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ZNF580 Double Nickase Plasmid (h) - sc-406194-NIC from Santa Cruz Biotechnology
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ZNF580 Double Nickase Plasmid (h2) - sc-406194-NIC-2 from Santa Cruz Biotechnology
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ZNF580 CRISPR Activation Plasmid (h) - sc-406194-ACT from Santa Cruz Biotechnology
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ZNF580 CRISPR Activation Plasmid (h2) - sc-406194-ACT-2 from Santa Cruz Biotechnology
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ZNF580 Lentiviral Activation Particles (h) - sc-406194-LAC from Santa Cruz Biotechnology
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ZNF580 Lentiviral Activation Particles (h2) - sc-406194-LAC-2 from Santa Cruz Biotechnology
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ZNF580 siRNA (h) - sc-97913 from Santa Cruz Biotechnology
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ZNF580 shRNA Plasmid (h) - sc-97913-SH from Santa Cruz Biotechnology
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ZNF580 shRNA (h) Lentiviral Particles - sc-97913-V from Santa Cruz Biotechnology
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ZNF580 RNAi - H00051157-R01 from Novus Biologicals
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ZNF580 RNAi - H00051157-R02 from Novus Biologicals
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MISSION® esiRNA - EHU226641 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN23561 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND23561 from Sigma-Aldrich
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ZNF580 siRNA (Human) - CRH9570 from Cohesion Biosciences
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ZNF580 - MBS8213305 from MyBioSource
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ZNF580 CRISPR/Cas9 KO Plasmid (h2) - sc-406194-KO-2 from Santa Cruz Biotechnology
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ZNF580 HDR Plasmid (h2) - sc-406194-HDR-2 from Santa Cruz Biotechnology
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shRNA set against Human ZNF580 (NM_016202.2) - SHH454492 from Creative biogene
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Human ZNF580 siRNA - orb270072 from Biorbyt
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ZNF580 shRNA Plasmid (Human) - CHH9570 from Cohesion Biosciences
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ZNF580 miRNA 3'UTR clone - MiUTR1H-11652 from Creative biogene
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ZNF580 miRNA 3'UTR clone - MiUTR3H-16855 from Creative biogene
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