Gene Symbol |
SPRED3
|
Entrez Gene |
399473
|
Alt Symbol |
Eve-3, spred-3
|
Species |
Human
|
Gene Type |
protein-coding
|
Description |
sprouty-related, EVH1 domain containing 3
|
Other Description |
sprouty-related, EVH1 domain-containing protein 3
|
Swissprots |
Q2MJR1 Q2MJR0
|
Accessions |
Q2MJR0 AI028379 AI871425 BC151136 AAI51137 BF983829 DQ323927 ABC54711 DQ323928 ABC54712 HG510783 XM_006723219 XP_006723282 XM_011526976 XP_011525278 XM_011526977 XP_011525279 XM_011526978 XP_011525280 XM_011526979 XP_011525281 NM_001042522 NP_001035987 NR_073032 NM_001039616
|
Function |
Tyrosine kinase substrate that inhibits growth-factor- mediated activation of MAP kinase. {ECO:0000250}.
|
Subcellular Location |
Membrane {ECO:0000250}; Peripheral membrane protein {ECO:0000250}.
|
Tissue Specificity |
Expression is restricted to liver. {ECO:0000269|PubMed:16478641}.
|
Top Pathways |
Jak-STAT signaling pathway
|