Gene Symbol | SPRED3 |
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Entrez Gene | 399473 |
Alt Symbol | Eve-3, spred-3 |
Species | Human |
Gene Type | protein-coding |
Description | sprouty-related, EVH1 domain containing 3 |
Other Description | sprouty-related, EVH1 domain-containing protein 3 |
Swissprots | Q2MJR1 Q2MJR0 |
Accessions | Q2MJR0 AI028379 AI871425 BC151136 AAI51137 BF983829 DQ323927 ABC54711 DQ323928 ABC54712 HG510783 XM_006723219 XP_006723282 XM_011526976 XP_011525278 XM_011526977 XP_011525279 XM_011526978 XP_011525280 XM_011526979 XP_011525281 NM_001042522 NP_001035987 NR_073032 NM_001039616 |
Function | Tyrosine kinase substrate that inhibits growth-factor- mediated activation of MAP kinase. {ECO:0000250}. |
Subcellular Location | Membrane {ECO:0000250}; Peripheral membrane protein {ECO:0000250}. |
Tissue Specificity | Expression is restricted to liver. {ECO:0000269|PubMed:16478641}. |
Top Pathways | Jak-STAT signaling pathway |
SPRED3 CRISPR/Cas9 KO Plasmid (h) - sc-406652 from Santa Cruz Biotechnology
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SPRED3 HDR Plasmid (h) - sc-406652-HDR from Santa Cruz Biotechnology
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SPRED3 Double Nickase Plasmid (h) - sc-406652-NIC from Santa Cruz Biotechnology
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SPRED3 Double Nickase Plasmid (h2) - sc-406652-NIC-2 from Santa Cruz Biotechnology
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SPRED3 CRISPR Activation Plasmid (h) - sc-406652-ACT from Santa Cruz Biotechnology
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SPRED3 CRISPR Activation Plasmid (h2) - sc-406652-ACT-2 from Santa Cruz Biotechnology
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SPRED3 Lentiviral Activation Particles (h) - sc-406652-LAC from Santa Cruz Biotechnology
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SPRED3 Lentiviral Activation Particles (h2) - sc-406652-LAC-2 from Santa Cruz Biotechnology
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SPRED3 siRNA (h) - sc-97920 from Santa Cruz Biotechnology
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SPRED3 shRNA Plasmid (h) - sc-97920-SH from Santa Cruz Biotechnology
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SPRED3 shRNA (h) Lentiviral Particles - sc-97920-V from Santa Cruz Biotechnology
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MISSION® esiRNA - EHU150361 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN20515 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND20515 from Sigma-Aldrich
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SPRED3 siRNA (Human) - CRJ8052 from Cohesion Biosciences
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SPRED3 - MBS8217039 from MyBioSource
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shRNA set against Human Spred3 (NM_001042522.2) - SHH417200 from Creative biogene
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Human SPRED3 siRNA - orb278553 from Biorbyt
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SPRED3 shRNA Plasmid (Human) - CHJ8052 from Cohesion Biosciences
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