Gene Symbol | CLEC10A |
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Entrez Gene | 10462 |
Alt Symbol | CD301, CLECSF13, CLECSF14, HML, HML2, MGL |
Species | Human |
Gene Type | protein-coding |
Description | C-type lectin domain family 10, member A |
Other Description | C-type (calcium dependent, carbohydrate-recognition domain) lectin, superfamily member 13 (macrophage-derived)|C-type (calcium dependent, carbohydrate-recognition domain) lectin, superfamily member 14 (macrophage-derived)|C-type lectin domain family 10 member A|macrophage lectin 2 (calcium dependent) |
Swissprots | Q8IUN9 Q6PIW3 Q14538 A8K8J8 |
Accessions | EAW90265 EAW90266 EAW90267 Q8IUN9 AK291975 BAF84664 AK292363 BAF85052 AL546075 BC027858 AAH27858 BC039011 AAH39011 BI910082 BM974488 BU687211 D50532 BAA09101 XM_005256412 XP_005256469 XM_011523613 XP_011521915 XM_011523614 XP_011521916 XM_011523615 XP_011521917 NM_006344 NP_006335 NM_182906 NP_878910 |
Function | Probable role in regulating adaptive and innate immune responses. Binds in a calcium-dependent manner to terminal galactose and N-acetylgalactosamine units, linked to serine or threonine. These sugar moieties are known as Tn-Ag and are expressed in a variety of carcinoma cells. {ECO:0000269|PubMed:8598452}. |
Subcellular Location | Membrane {ECO:0000305}; Single-pass type II membrane protein {ECO:0000305}. |
CLEC-10A CRISPR/Cas9 KO Plasmid (h) - sc-411473 from Santa Cruz Biotechnology
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CLEC-10A HDR Plasmid (h) - sc-411473-HDR from Santa Cruz Biotechnology
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CLEC-10A Double Nickase Plasmid (h) - sc-411473-NIC from Santa Cruz Biotechnology
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CLEC-10A Double Nickase Plasmid (h2) - sc-411473-NIC-2 from Santa Cruz Biotechnology
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CLEC-10A CRISPR Activation Plasmid (h) - sc-411473-ACT from Santa Cruz Biotechnology
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CLEC-10A CRISPR Activation Plasmid (h2) - sc-411473-ACT-2 from Santa Cruz Biotechnology
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CLEC-10A Lentiviral Activation Particles (h) - sc-411473-LAC from Santa Cruz Biotechnology
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CLEC-10A Lentiviral Activation Particles (h2) - sc-411473-LAC-2 from Santa Cruz Biotechnology
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CLEC-10A siRNA (h) - sc-94237 from Santa Cruz Biotechnology
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CLEC-10A shRNA Plasmid (h) - sc-94237-SH from Santa Cruz Biotechnology
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CLEC-10A shRNA (h) Lentiviral Particles - sc-94237-V from Santa Cruz Biotechnology
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MISSION® esiRNA - EHU146341 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN6196 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND6196 from Sigma-Aldrich
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CLEC10A siRNA (Human) - CRH7100 from Cohesion Biosciences
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CLEC10A - MBS8222663 from MyBioSource
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shRNA set against Human CLEC10A (NM_182906.2) - SHH264893 from Creative biogene
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shRNA set against Human CLEC10A(NM_006344.2) - SHG181081 from Creative biogene
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shRNA set against Human CLEC10A(NM_182906.2) - SHG181135 from Creative biogene
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Human CLEC10A siRNA - orb267602 from Biorbyt
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CLEC10A shRNA Plasmid (Human) - CHH7100 from Cohesion Biosciences
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CLEC10A miRNA 3'UTR clone - MiUTR1H-02198 from Creative biogene
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CLEC10A miRNA 3'UTR clone - MiUTR1H-02199 from Creative biogene
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