Gene Symbol | ACTN2 |
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Entrez Gene | 88 |
Alt Symbol | CMD1AA |
Species | Human |
Gene Type | protein-coding |
Description | actinin, alpha 2 |
Other Description | F-actin cross-linking protein|alpha-actinin skeletal muscle|alpha-actinin-2 |
Swissprots | B1ANE4 P35609 Q86TF4 B2RCS5 Q86TI8 |
Accessions | AAA51584 CAB61269 EAW70064 EAW70065 P35609 AB209521 BAD92758 AK294906 BAH11921 AK297469 BAH12587 AK297618 BAH12632 AK297628 BAH12634 AK297886 BAH12687 AK315250 BAG37672 BC047901 AAH47901 BC051770 AAH51770 BX103017 CB153006 DC378038 M86406 AAA51583 NM_001103 NP_001094 NM_001278343 NP_001265272 NM_001278344 NP_001265273 |
Function | F-actin cross-linking protein which is thought to anchor actin to a variety of intracellular structures. This is a bundling protein. |
Subcellular Location | Cytoplasm, myofibril, sarcomere, Z line {ECO:0000269|PubMed:11171996, ECO:0000269|PubMed:19932097}. Note=Colocalizes with MYOZ1 and FLNC at the Z-lines of skeletal muscle. |
Tissue Specificity | Expressed in both skeletal and cardiac muscle. |
Top Pathways | Systemic lupus erythematosus, Adherens junction, Arrhythmogenic right ventricular cardiomyopathy (ARVC), Leukocyte transendothelial migration, Amoebiasis |
Human Sarcomeric Alpha Actinin peptide - ab100828 from Abcam
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Human Sarcomeric Alpha Actinin protein fragment - ab92234 from Abcam
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ACTN2 Antibody Blocking Peptide - LS-E3740 from LifeSpan Bioscience
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ACTN2 Antibody Blocking Peptide - LS-E13416 from LifeSpan Bioscience
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ACTN2 Antibody Blocking Peptide - LS-E15261 from LifeSpan Bioscience
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ACTN2 Antibody Blocking Peptide - LS-E15260 from LifeSpan Bioscience
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ACTN2-Antibody-C-term-Blocking-Peptide - BP14950b from Abgent, a WuXi AppTec company
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ACTN2 Protein Lysate (APL10612) - APL10612 from Aviva Systems Biology
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ACTN2 Protein Lysate (APL10718) - APL10718 from Aviva Systems Biology
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ACTN2 Protein Lysate (APL10822) - APL10822 from Aviva Systems Biology
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ACTN2 Protein Lysate (APL10823) - APL10823 from Aviva Systems Biology
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ACTN2 Protein Lysate (APL10824) - APL10824 from Aviva Systems Biology
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ACTN2 Blocking Peptide - 33R-4126 from Fitzgerald
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alpha Actinin 2 Blocking Peptide - 33R-6838 from Fitzgerald
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alpha Actinin 2 Blocking Peptide - 33R-9587 from Fitzgerald
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ACTN2 Blocking Peptide - abx062206 from Abbexa
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ACTN2 fusion protein - ag5578 from Proteintech Group
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ACTN2 fusion protein - Ag5459 from Proteintech Group
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Recombinant Human ACTN2, His-tagged - ACTN2-31382TH from Creative Biomart
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Recombinant Actinin Alpha 2 (ACTN2) - RPA376Hu01 from Uscn Life Science Inc.
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Recombinant Actinin Alpha 2 (ACTN2) - RPA376Mu01 from Uscn Life Science Inc.
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ACTN2 Blocking Peptide - CBP1012 from Cohesion Biosciences
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Actinin-α2/3 (Q58) Peptide - BS1984P from Bioworld Technology
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Recombinant Human Alpha-actinin-2(ACTN2) ,partial - CSB-YP001242HU CSB-EP001242HU CSB-BP001242HU CSB-MP001242HU from Cusabio
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Alpha-actinin-2(ACTN2) ,partial - MBS955256 from MyBioSource
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