| Gene Symbol | FBN3 |
|---|---|
| Entrez Gene | 84467 |
| Alt Symbol | - |
| Species | Human |
| Gene Type | protein-coding |
| Description | fibrillin 3 |
| Other Description | fibrillin-3 |
| Swissprots | Q96JP8 Q75N91 Q86SJ5 Q75N93 Q75N90 Q75N92 |
| Accessions | BAD16733 BAD16734 BAD16735 BAD16736 EAW68946 EAW68947 EAW68948 Q75N90 AB053450 BAB47408 AI341180 AK000036 AK074501 AK095563 BAG53085 AK096539 BAG53318 AK131282 BAD18457 AY165863 AAO18145 AY165864 AAO18146 AY165865 AAO18147 BC153882 AAI53883 CD634017 CN369190 XM_011528373 XP_011526675 NM_032447 NP_115823 |
| Function | Fibrillins are structural components of 10-12 nm extracellular calcium-binding microfibrils, which occur either in association with elastin or in elastin-free bundles. Fibrillin- containing microfibrils provide long-term force bearing structural support. {ECO:0000269|PubMed:14962672}. |
| Subcellular Location | Secreted, extracellular space, extracellular matrix {ECO:0000269|PubMed:14962672}. |
| Tissue Specificity | Predominantly expressed in connective tissues such as skeletal muscle, tendon, skin, perichondrium and periosteum. Highly expressed in fetal lung, brain, kidney. Expressed at low level in prostate, testis, mammary gland, uterus, ovary, placenta, bladder, adrenal gland, thyroid, fetal thymus, fetal liver, liver, fetal heart and heart. {ECO:0000269|PubMed:14962672}. |
Panoply™ Human FBN3 Knockdown Stable Cell Line - CSC-DC005562 from Creative biogene
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