Gene Symbol |
GTF2E2
|
Entrez Gene |
2961
|
Alt Symbol |
FE, TF2E2, TFIIE-B
|
Species |
Human
|
Gene Type |
protein-coding
|
Description |
general transcription factor IIE, polypeptide 2, beta 34kDa
|
Other Description |
TFIIE-beta|general transcription factor IIE subunit 2|transcription initiation factor IIE subunit beta
|
Swissprots |
P29084 Q9H2B9 D3DSV2
|
Accessions |
AAG39077 EAW63446 EAW63447 EAW63448 EAW63449 P29084 BC001775 BC030572 AAH30572 S67861 AAB20414 X63469 CAA45069 XM_011544509 XP_011542811 XM_011544510 XP_011542812 NM_002095 NP_002086
|
Function |
Recruits TFIIH to the initiation complex and stimulates the RNA polymerase II C-terminal domain kinase and DNA-dependent ATPase activities of TFIIH. Both TFIIH and TFIIE are required for promoter clearance by RNA polymerase.
|
Subcellular Location |
Nucleus.
|
Top Pathways |
Viral carcinogenesis, Epstein-Barr virus infection, Basal transcription factors
|