Gene Symbol | GTF2E2 |
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Entrez Gene | 2961 |
Alt Symbol | FE, TF2E2, TFIIE-B |
Species | Human |
Gene Type | protein-coding |
Description | general transcription factor IIE, polypeptide 2, beta 34kDa |
Other Description | TFIIE-beta|general transcription factor IIE subunit 2|transcription initiation factor IIE subunit beta |
Swissprots | P29084 Q9H2B9 D3DSV2 |
Accessions | AAG39077 EAW63446 EAW63447 EAW63448 EAW63449 P29084 BC001775 BC030572 AAH30572 S67861 AAB20414 X63469 CAA45069 XM_011544509 XP_011542811 XM_011544510 XP_011542812 NM_002095 NP_002086 |
Function | Recruits TFIIH to the initiation complex and stimulates the RNA polymerase II C-terminal domain kinase and DNA-dependent ATPase activities of TFIIH. Both TFIIH and TFIIE are required for promoter clearance by RNA polymerase. |
Subcellular Location | Nucleus. |
Top Pathways | Viral carcinogenesis, Epstein-Barr virus infection, Basal transcription factors |
TFIIE-β siRNA (h) - sc-36650 from Santa Cruz Biotechnology
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TFIIE-β shRNA Plasmid (h) - sc-36650-SH from Santa Cruz Biotechnology
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TFIIE-β shRNA (h) Lentiviral Particles - sc-36650-V from Santa Cruz Biotechnology
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TFIIE beta RNAi - H00002961-R01 from Novus Biologicals
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MISSION® esiRNA - EHU019681 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN9758 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND9758 from Sigma-Aldrich
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MISSION® 3′UTR Lenti GoClone™ - HUTR03427 from Sigma-Aldrich
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GTF2E2 siRNA (Human) - CRH2004 from Cohesion Biosciences
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GTF2E2 - MBS8208144 from MyBioSource
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shRNA set against Human GTF2E2 (NM_002095.4) - SHH308882 from Creative biogene
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shRNA set against Human GTF2E2(NM_002095.4) - SHH108515 from Creative biogene
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GTF2E2 shRNA Plasmid (Human) - CHH2004 from Cohesion Biosciences
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GTF2E2 miRNA 3'UTR clone - MiUTR1H-04318 from Creative biogene
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