CHIT1

Gene Symbol CHIT1
Entrez Gene 1118
Alt Symbol CHI3, CHIT, CHITD
Species Human
Gene Type protein-coding
Description chitinase 1 (chitotriosidase)
Other Description chitotriosidase-1|plasma methylumbelliferyl tetra-N-acetylchitotetraoside hydrolase
Swissprots Q0VGG6 B3KNW6 Q9H3V8 Q0VGG5 Q13231 Q6ISC2 Q9UDJ8 J3KN09 Q3ZAR1
Accessions EAW91469 EAW91470 EAW91471 Q13231 AI697695 AK055165 BAG51478 AK131093 BAC85143 AK225245 AK309341 AK314331 BC069614 AAH69614 BC103695 AAI03696 BC105680 AAI05681 BC105681 AAI05682 BC105682 AAI05683 BP297140 BP304256 BQ029424 BX096812 BX099272 U29615 AAC50246 U62662 AAG10644 XM_011509109 XP_011507411 XM_011509110 XP_011507412 XR_921732 NM_001256125 NP_001243054 NM_001270509 NP_001257438 NM_003465 NP_003456 NR_045784 NR_045785
Function Degrades chitin, chitotriose and chitobiose. May participate in the defense against nematodes and other pathogens. Isoform 3 has no enzymatic activity. {ECO:0000269|PubMed:7592832, ECO:0000269|PubMed:7836450}.
Subcellular Location Secreted. Lysosome. Note=A small proportion is lysosomal.
Tissue Specificity Detected in spleen. Secreted by cultured macrophages. {ECO:0000269|PubMed:7836450}.
Top Pathways Amino sugar and nucleotide sugar metabolism

Chitotriosidase (A-11) - sc-271460 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
Chitotriosidase (A-11): sc-271460. Immunofluorescence staining of methanol-fixed HeLa cells showing cytoplasmic localization.

Chitotriosidase (A-3) - sc-271282 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
Chitotriosidase (A-3): sc-271282. Western blot analysis of Chitotriosidase expression in AML-193 whole cell lysate.

Chitotriosidase (C-18) - sc-46855 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal
Chitotriosidase (C-18): sc-46855. Immunoperoxidase staining of formalin fixed, paraffin-embedded human lymph node tissue showing cytoplasmic staining of cells in germinal centers and cells in non-germinal centers.

Chitotriosidase (H-66) - sc-99033 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Rabbit
Clonality Polyclonal
Chitotriosidase (H-66): sc-99033. Western blot analysis of Chitotriosidase expression in AML-193 whole cell lysate.

Chitotriosidase (N-16) - sc-46858 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal
Chitotriosidase (N-16): sc-46858. Western blot analysis of Chitotriosidase expression in Hep G2 whole cell lysate.

Chitotriosidase (C-17) - sc-46854 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal
Chitotriosidase (C-17): sc-46854. Western blot analysis of Chitotriosidase expression in Hep G2 (A), HeLa (B) and U-251-MG (C) whole cell lysates.

Anti-CHIT1 antibody - ab72574 from Abcam

Prices $370.00
Sizes 50 µg
Host Mouse
Clonality Polyclonal
All lanes : Anti-CHIT1 antibody (ab72574) at 1/500 dilutionLane 1 : CHIT1 transfected 293T cell lysateLane 2 : non-transfected 293T cell lysateLysates/proteins at 25 µg per lane.SecondaryGoat Anti-mouse (H&L)-HRP Conjugated IgG at 1/2500 dilution

Anti-CHIT1 antibody - ab96045 from Abcam

Prices $370.00
Sizes 50 µl
Host Rabbit
Clonality Polyclonal
Anti-CHIT1 antibody (ab96045) at 1/1000 dilution + HeLa whole cell lysate at 30 µg

Anti-CHIT1 antibody - ab126866 from Abcam

Prices $370.00
Sizes 200 µl
Host Goat
Clonality Polyclonal
Anti-CHIT1 antibody (ab126866) at 1 µg/ml + Daudi lysate at 35 µgdeveloped using the ECL technique

Anti-CHIT1 antibody - ab171768 from Abcam

Prices $370.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
All lanes : Anti-CHIT1 antibody (ab171768) at 1 µg/mlLane 1 : CHIT1 transfected 293T cell lysateLane 2 : Non-transfected 293T cell lysateLysates/proteins at 15 µl per lane.SecondaryGoat Anti-Rabbit IgG (H+L), Peroxidase Conjugated at 1/7500 dilution

Anti-CHIT1 antibody [1D9G2,1D9G4,2B4G3] - ab81613 from Abcam

Host Mouse
Clonality Monoclonal
Clone 1D9G2,1D9G4,2B4G3
All lanes : Anti-CHIT1 antibody [1D9G2,1D9G4,2B4G3] (ab81613) at 1/500 dilutionLane 1 : truncated Trx-CHIT1 recombinant protein Lane 2 : truncated CHIT1 (aa22-466)-hIgGFc transfected CHO-K1 cell lysate

Anti-CHIT1 / Chitotriosidase Antibody - LS-C35914 from LifeSpan Bioscience

Prices $425.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal

Anti-CHIT1 / Chitotriosidase Antibody (aa22-466) - LS-C35915 from LifeSpan Bioscience

Prices $465.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal

Anti-CHIT1 / Chitotriosidase Antibody - LS-C293305 from LifeSpan Bioscience

Prices $405.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal

Anti-CHIT1 / Chitotriosidase Antibody (Biotin) - LS-C299377 from LifeSpan Bioscience

Prices $435.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal

Anti-CHIT1 / Chitotriosidase Antibody (FITC) - LS-C305423 from LifeSpan Bioscience

Prices $455.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal

Anti-CHIT1 / Chitotriosidase Antibody - LS-C306941 from LifeSpan Bioscience

Prices $455.00
Sizes 50 µg
Host Mouse
Clonality Polyclonal

Anti-CHIT1 / Chitotriosidase Antibody - LS-C309901 from LifeSpan Bioscience

Prices $475.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal

Anti-CHIT1 / Chitotriosidase Antibody - LS-C341740 from LifeSpan Bioscience

Prices $385.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal

Anti-CHIT1 / Chitotriosidase Antibody (clone 1D9G2,1D9G4,2B4G3) - LS-C108782 from LifeSpan Bioscience

Prices $345.00
Sizes 100 µl
Host Mouse
Clonality Monoclonal
Clone 1D9G2,1D9G4,2B4G3
Western blot using CHIT1 mouse monoclonal antibody against truncated Trx-CHIT1 recombinant protein (1) and truncated CHIT1 (aa22-466)-hIgGFc transfected CHO-K1 cell lysate (2).

Anti-CHIT1 / Chitotriosidase Antibody (clone 1D11) - LS-C196908 from LifeSpan Bioscience

Prices $355.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
Clone 1D11
Detection limit for recombinant GST tagged CHIT1 is 0.03 ng/ml as a capture antibody.

Anti-CHIT1 / Chitotriosidase Antibody (aa216-463) - LS-C185418 from LifeSpan Bioscience

Prices $335.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Sample (30 ug of whole cell lysate). A: Hela. 10% SDS PAGE. CHIT1 / Chitotriosidase antibody diluted at 1:1000.

Anti-CHIT1 / Chitotriosidase Antibody (aa409-423) - LS-C154935 from LifeSpan Bioscience

Prices $395.00
Sizes 100 µg
Host Goat
Clonality Polyclonal
CHIT1 antibody (1 ug/ml) staining of Daudi lysate (35 ug protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.

Chitotriosidase/CHIT1 Antibody (397513) - MAB35591 from Novus Biologicals

Prices $99.00, $249.00
Sizes 25 µg, 100 µg
Host Mouse
Clonality Monoclonal
Clone 397513

Chitotriosidase/CHIT1 Antibody - AF3559 from Novus Biologicals

Prices $99.00, $359.00
Sizes 25 µg, 100 µg
Host Goat
Clonality Polyclonal
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