| Gene Symbol |
IL20RA
|
| Entrez Gene |
53832
|
| Alt Symbol |
CRF2-8, IL-20R-alpha, IL-20R1, IL-20RA
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
interleukin 20 receptor, alpha
|
| Other Description |
class II cytokine receptor ZCYTOR7|cytokine receptor family 2 member 8|interleukin-20 receptor I|interleukin-20 receptor subunit alpha
|
| Swissprots |
Q9UHF4 Q6UWA9 Q96SH8 Q14CW2 F5H675 B4DLR5
|
| Accessions |
CCQ43436 EAW47936 EAW47937 EAW47938 Q9UHF4 AF184971 AAF01320 AJ420490 AK098312 AK297121 BAG59627 AK307072 AK315293 BAG37699 AY358883 AAQ89242 BC113574 AAI13575 BC113602 AAI13603 BM713319 DN998331 HQ258452 ADR83206 HY009306 XM_006715505 XP_006715568 XM_006715506 XP_006715569 XM_011535904 XP_011534206 NM_001278722 NP_001265651 NM_001278723 NP_001265652 NM_001278724 NP_001265653 NM_014432 NP_055247
|
| Function |
The IL20RA/IL20RB dimer is a receptor for IL19, IL20 and IL24. The IL20RA/IL10RB dimer is a receptor for IL26.
|
| Subcellular Location |
Membrane {ECO:0000250}; Single-pass type I membrane protein {ECO:0000250}.
|
| Tissue Specificity |
Widely expressed with highest levels in skin and testis and high levels in brain. Highly expressed in psoriatic skin. {ECO:0000269|PubMed:11163236, ECO:0000269|PubMed:14764663}.
|
| Top Pathways |
Cytokine-cytokine receptor interaction, Jak-STAT signaling pathway
|