Gene Symbol | IL20RA |
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Entrez Gene | 53832 |
Alt Symbol | CRF2-8, IL-20R-alpha, IL-20R1, IL-20RA |
Species | Human |
Gene Type | protein-coding |
Description | interleukin 20 receptor, alpha |
Other Description | class II cytokine receptor ZCYTOR7|cytokine receptor family 2 member 8|interleukin-20 receptor I|interleukin-20 receptor subunit alpha |
Swissprots | Q9UHF4 Q6UWA9 Q96SH8 Q14CW2 F5H675 B4DLR5 |
Accessions | CCQ43436 EAW47936 EAW47937 EAW47938 Q9UHF4 AF184971 AAF01320 AJ420490 AK098312 AK297121 BAG59627 AK307072 AK315293 BAG37699 AY358883 AAQ89242 BC113574 AAI13575 BC113602 AAI13603 BM713319 DN998331 HQ258452 ADR83206 HY009306 XM_006715505 XP_006715568 XM_006715506 XP_006715569 XM_011535904 XP_011534206 NM_001278722 NP_001265651 NM_001278723 NP_001265652 NM_001278724 NP_001265653 NM_014432 NP_055247 |
Function | The IL20RA/IL20RB dimer is a receptor for IL19, IL20 and IL24. The IL20RA/IL10RB dimer is a receptor for IL26. |
Subcellular Location | Membrane {ECO:0000250}; Single-pass type I membrane protein {ECO:0000250}. |
Tissue Specificity | Widely expressed with highest levels in skin and testis and high levels in brain. Highly expressed in psoriatic skin. {ECO:0000269|PubMed:11163236, ECO:0000269|PubMed:14764663}. |
Top Pathways | Cytokine-cytokine receptor interaction, Jak-STAT signaling pathway |
IL-20Rα CRISPR/Cas9 KO Plasmid (h) - sc-405034 from Santa Cruz Biotechnology
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IL-20Rα HDR Plasmid (h) - sc-405034-HDR from Santa Cruz Biotechnology
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IL-20Rα Double Nickase Plasmid (h) - sc-405034-NIC from Santa Cruz Biotechnology
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IL-20Rα Double Nickase Plasmid (h2) - sc-405034-NIC-2 from Santa Cruz Biotechnology
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IL-20Rα CRISPR Activation Plasmid (h) - sc-405034-ACT from Santa Cruz Biotechnology
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IL-20Rα CRISPR Activation Plasmid (h2) - sc-405034-ACT-2 from Santa Cruz Biotechnology
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IL-20Rα Lentiviral Activation Particles (h) - sc-405034-LAC from Santa Cruz Biotechnology
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IL-20Rα Lentiviral Activation Particles (h2) - sc-405034-LAC-2 from Santa Cruz Biotechnology
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IL-20Rα siRNA (h) - sc-45237 from Santa Cruz Biotechnology
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IL-20Rα shRNA Plasmid (h) - sc-45237-SH from Santa Cruz Biotechnology
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IL-20Rα shRNA (h) Lentiviral Particles - sc-45237-V from Santa Cruz Biotechnology
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IL-20 R alpha RNAi - H00053832-R02 from Novus Biologicals
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CompoZr® Knockout ZFN Kit - CKOZFN10605 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND10605 from Sigma-Aldrich
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MISSION® 3′UTR Lenti GoClone™ - HUTR09810 from Sigma-Aldrich
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IL20RA siRNA (Human) - CRH9987 from Cohesion Biosciences
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IL20RA - MBS8214326 from MyBioSource
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shRNA set against Human Il20ra (NM_014432.2) - SHH318665 from Creative biogene
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shRNA set against Human IL20RA(NM_014432.2) - SHL134688 from Creative biogene
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IL20RA shRNA Plasmid (Human) - CHH9987 from Cohesion Biosciences
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IL20RA miRNA 3'UTR clone - MiUTR1H-04905 from Creative biogene
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