| Gene Symbol |
MGST3
|
| Entrez Gene |
4259
|
| Alt Symbol |
GST-III
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
microsomal glutathione S-transferase 3
|
| Other Description |
microsomal GST-3|microsomal GST-III|microsomal glutathione S-transferase III
|
| Swissprots |
O14880 Q6ICN4 B2R592
|
| Accessions |
AAQ81301 EAW90752 EAW90753 EAW90754 EAW90755 EAW90756 EAW90757 O14880 AF026977 AAB82609 AI591182 AK223012 BAD96732 AK312103 BAG35039 BC000505 AAH00505 BC003034 AAH03034 BC005964 AAH05964 BI666647 CR450359 CAG29355 DQ185045 ABD14425 HQ448709 ADQ33187 JF432565 ADZ15782 XM_005245174 XP_005245231 NM_004528 NP_004519
|
| Function |
Also functions as a glutathione peroxidase.
|
| Subcellular Location |
Endoplasmic reticulum membrane {ECO:0000305}; Multi-pass membrane protein {ECO:0000305}. Microsome membrane {ECO:0000305}; Multi-pass membrane protein {ECO:0000305}. Microsome membrane {ECO:0000305}; Lipid-anchor {ECO:0000305}.
|
| Tissue Specificity |
Predominantly expressed in heart, skeletal muscle, and adrenal cortex. Also found in brain, placenta, liver, kidney, pancreas, thyroid, testis and ovary. Almost absent in lung, thymus and peripheral blood leukocytes.
|
| Top Pathways |
Chemical carcinogenesis, Glutathione metabolism, Metabolism of xenobiotics by cytochrome P450, Drug metabolism - cytochrome P450
|