Gene Symbol | MGST3 |
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Entrez Gene | 4259 |
Alt Symbol | GST-III |
Species | Human |
Gene Type | protein-coding |
Description | microsomal glutathione S-transferase 3 |
Other Description | microsomal GST-3|microsomal GST-III|microsomal glutathione S-transferase III |
Swissprots | O14880 Q6ICN4 B2R592 |
Accessions | AAQ81301 EAW90752 EAW90753 EAW90754 EAW90755 EAW90756 EAW90757 O14880 AF026977 AAB82609 AI591182 AK223012 BAD96732 AK312103 BAG35039 BC000505 AAH00505 BC003034 AAH03034 BC005964 AAH05964 BI666647 CR450359 CAG29355 DQ185045 ABD14425 HQ448709 ADQ33187 JF432565 ADZ15782 XM_005245174 XP_005245231 NM_004528 NP_004519 |
Function | Also functions as a glutathione peroxidase. |
Subcellular Location | Endoplasmic reticulum membrane {ECO:0000305}; Multi-pass membrane protein {ECO:0000305}. Microsome membrane {ECO:0000305}; Multi-pass membrane protein {ECO:0000305}. Microsome membrane {ECO:0000305}; Lipid-anchor {ECO:0000305}. |
Tissue Specificity | Predominantly expressed in heart, skeletal muscle, and adrenal cortex. Also found in brain, placenta, liver, kidney, pancreas, thyroid, testis and ovary. Almost absent in lung, thymus and peripheral blood leukocytes. |
Top Pathways | Chemical carcinogenesis, Glutathione metabolism, Metabolism of xenobiotics by cytochrome P450, Drug metabolism - cytochrome P450 |
MGST3 CRISPR/Cas9 KO Plasmid (h) - sc-410885 from Santa Cruz Biotechnology
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MGST3 HDR Plasmid (h) - sc-410885-HDR from Santa Cruz Biotechnology
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MGST3 Double Nickase Plasmid (h) - sc-410885-NIC from Santa Cruz Biotechnology
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MGST3 Double Nickase Plasmid (h2) - sc-410885-NIC-2 from Santa Cruz Biotechnology
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MGST3 CRISPR Activation Plasmid (h) - sc-410885-ACT from Santa Cruz Biotechnology
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MGST3 CRISPR Activation Plasmid (h2) - sc-410885-ACT-2 from Santa Cruz Biotechnology
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MGST3 Lentiviral Activation Particles (h) - sc-410885-LAC from Santa Cruz Biotechnology
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MGST3 Lentiviral Activation Particles (h2) - sc-410885-LAC-2 from Santa Cruz Biotechnology
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MGST3 siRNA (h) - sc-62612 from Santa Cruz Biotechnology
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MGST3 shRNA Plasmid (h) - sc-62612-SH from Santa Cruz Biotechnology
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MGST3 shRNA (h) Lentiviral Particles - sc-62612-V from Santa Cruz Biotechnology
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MGST3 RNAi - H00004259-R01 from Novus Biologicals
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MISSION® esiRNA - EHU056111 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN13308 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND13308 from Sigma-Aldrich
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MISSION® 3′UTR Lenti GoClone™ - HUTR00059 from Sigma-Aldrich
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MGST3 siRNA (Human) - CRH2897 from Cohesion Biosciences
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shRNA set against Human MGST3 (NM_004528.3) - SHH341743 from Creative biogene
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Human MGST3 siRNA - orb263399 from Biorbyt
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MGST3 shRNA Plasmid (Human) - CHH2897 from Cohesion Biosciences
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MGST3 miRNA 3'UTR clone - MiUTR3H-06916 from Creative biogene
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