| Gene Symbol |
PHB
|
| Entrez Gene |
5245
|
| Alt Symbol |
HEL-215, HEL-S-54e, PHB1
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
prohibitin
|
| Other Description |
epididymis luminal protein 215|epididymis secretory sperm binding protein Li 54e
|
| Swissprots |
P35232 B4DY47 Q4VBQ0
|
| Accessions |
AAA86691 AAO18340 CAL48156 EAW94680 EAW94681 P35232 AA357151 AA709387 AK223181 BAD96901 AK290766 BAF83455 AK302258 BAG63609 AK307767 AK312649 BAG35532 AM393620 CAL38496 AY577780 AAS88903 BC013401 AAH13401 BC095460 AAH95460 BE729762 BF038604 BG029858 BI871461 BM972128 BP267961 BQ574485 BT007411 AAP36079 CR541706 CAG46507 CX784018 DC360133 FJ224341 ACI46033 FJ460516 ACS44653 S85655 AAB21614 NM_001281496 NP_001268425 NM_001281497 NP_001268426 NM_001281715 NP_001268644 NM_002634 NP_002625
|
| Function |
Prohibitin inhibits DNA synthesis. It has a role in regulating proliferation. As yet it is unclear if the protein or the mRNA exhibits this effect. May play a role in regulating mitochondrial respiration activity and in aging. {ECO:0000269|PubMed:11302691}.
|
| Subcellular Location |
Mitochondrion inner membrane {ECO:0000250}.
|
| Tissue Specificity |
Widely expressed in different tissues.
|
![Western Blot: Prohibitin Overexpression Lysate (Adult Normal) [NBL1-14348] Left-Empty vector transfected control cell lysate (HEK293 cell lysate); Right -Over-expression Lysate for Prohibitin.](http://www.bioprodhub.com/system/product_images/cel_products/5/sub_2/4253_Prohibitin%2520Overexpression%2520Lysate%2520(Adult%2520Normal)-Western%2520Blot-NBL1-14348-img0002.jpg)