| Gene Symbol |
Bag1
|
| Entrez Gene |
297994
|
| Alt Symbol |
Bag-1
|
| Species |
Rat
|
| Gene Type |
protein-coding
|
| Description |
BCL2-associated athanogene
|
| Other Description |
BAG family molecular chaperone regulator 1|bcl-2-associated athanogene 1
|
| Swissprots |
B0K019
|
| Accessions |
B0K019 EDL98648 EDL98649 EDL98650 BC159418 AAI59419 BF523560 BI280304 DY309876 FQ215132 FQ224976 NM_001106647 NP_001100117 NM_001256084 NP_001243013
|
| Function |
Inhibits the chaperone activity of HSP70/HSC70 by promoting substrate release. Inhibits the pro-apoptotic function of PPP1R15A, and has anti-apoptotic activity. Markedly increases the anti-cell death function of BCL2 induced by various stimuli (By similarity). {ECO:0000250}.
|
| Subcellular Location |
Nucleus {ECO:0000250}. Cytoplasm {ECO:0000250}.
|
| Top Pathways |
Protein processing in endoplasmic reticulum
|