Gene Symbol | Bag1 |
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Entrez Gene | 297994 |
Alt Symbol | Bag-1 |
Species | Rat |
Gene Type | protein-coding |
Description | BCL2-associated athanogene |
Other Description | BAG family molecular chaperone regulator 1|bcl-2-associated athanogene 1 |
Swissprots | B0K019 |
Accessions | B0K019 EDL98648 EDL98649 EDL98650 BC159418 AAI59419 BF523560 BI280304 DY309876 FQ215132 FQ224976 NM_001106647 NP_001100117 NM_001256084 NP_001243013 |
Function | Inhibits the chaperone activity of HSP70/HSC70 by promoting substrate release. Inhibits the pro-apoptotic function of PPP1R15A, and has anti-apoptotic activity. Markedly increases the anti-cell death function of BCL2 induced by various stimuli (By similarity). {ECO:0000250}. |
Subcellular Location | Nucleus {ECO:0000250}. Cytoplasm {ECO:0000250}. |
Top Pathways | Protein processing in endoplasmic reticulum |
Bag-1 siRNA (r) - sc-61877 from Santa Cruz Biotechnology
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Bag-1 shRNA Plasmid (r) - sc-61877-SH from Santa Cruz Biotechnology
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CompoZr® Knockout ZFN Kit - CKOZFN51065 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND51065 from Sigma-Aldrich
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BAG1 siRNA (Rat) - CRR4546 from Cohesion Biosciences
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BAG1 - MBS827062 from MyBioSource
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shRNA set against Rat BAG1 (NM_001106647.3) - SHH244626 from Creative biogene
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Rat BAG1 siRNA - orb299395 from Biorbyt
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BAG1 shRNA Plasmid (Rat) - CHR4546 from Cohesion Biosciences
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