Gene Symbol | ITGA9 |
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Entrez Gene | 3680 |
Alt Symbol | ALPHA-RLC, ITGA4L, RLC |
Species | Human |
Gene Type | protein-coding |
Description | integrin, alpha 9 |
Other Description | integrin alpha-9|integrin alpha-RLC |
Swissprots | Q13797 Q14638 |
Accessions | CCQ43170 EAW64501 Q13797 AK026826 AK123884 BC030198 AAH30198 BX647350 D25303 BAA04984 L24158 AAA16099 NM_002207 NP_002198 |
Function | Integrin alpha-9/beta-1 (ITGA9:ITGB1) is a receptor for VCAM1, cytotactin and osteopontin. It recognizes the sequence A-E- I-D-G-I-E-L in cytotactin. {ECO:0000250}. |
Subcellular Location | Membrane {ECO:0000255}; Single-pass type I membrane protein {ECO:0000255}. |
Tissue Specificity | In airway epithelium, in the basal layer of squamous epithelium, and in smooth muscle, skeletal muscle, and hepatocytes. Abundantly expressed in fetal lung and lung cancers. {ECO:0000269|PubMed:8245132, ECO:0000269|PubMed:8290272}. |
Top Pathways | Focal adhesion, ECM-receptor interaction, Cell adhesion molecules (CAMs), Hypertrophic cardiomyopathy (HCM), Arrhythmogenic right ventricular cardiomyopathy (ARVC) |
Integrin α9 CRISPR/Cas9 KO Plasmid (h) - sc-402221 from Santa Cruz Biotechnology
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Integrin α9 HDR Plasmid (h) - sc-402221-HDR from Santa Cruz Biotechnology
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Integrin α9 Double Nickase Plasmid (h) - sc-402221-NIC from Santa Cruz Biotechnology
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Integrin α9 Double Nickase Plasmid (h2) - sc-402221-NIC-2 from Santa Cruz Biotechnology
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Integrin α9 CRISPR Activation Plasmid (h) - sc-402221-ACT from Santa Cruz Biotechnology
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Integrin α9 CRISPR Activation Plasmid (h2) - sc-402221-ACT-2 from Santa Cruz Biotechnology
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Integrin α9 Lentiviral Activation Particles (h) - sc-402221-LAC from Santa Cruz Biotechnology
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Integrin α9 Lentiviral Activation Particles (h2) - sc-402221-LAC-2 from Santa Cruz Biotechnology
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Integrin α9 siRNA (h) - sc-75340 from Santa Cruz Biotechnology
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Integrin a9 shRNA Plasmid (h) - sc-75340-SH from Santa Cruz Biotechnology
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Integrin a9 shRNA (h) Lentiviral Particles - sc-75340-V from Santa Cruz Biotechnology
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MISSION® esiRNA - EHU131561 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN10811 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND10811 from Sigma-Aldrich
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MISSION® 3′UTR Lenti GoClone™ - HUTR06953 from Sigma-Aldrich
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ITGA9 siRNA (Human) - CRH2470 from Cohesion Biosciences
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Integrin alpha 9 RNAi - H00003680-R02 from Novus Biologicals
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ITGA9 - MBS8213750 from MyBioSource
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shRNA set against Human ITGA9 (NM_002207.2) - SHH321257 from Creative biogene
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shRNA set against Human ITGA9(NM_002207.2) - SHL181722 from Creative biogene
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ITGA9 shRNA Plasmid (Human) - CHH2470 from Cohesion Biosciences
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ITGA9 miRNA 3'UTR clone - MiUTR1H-05026 from Creative biogene
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