| Gene Symbol |
MRPL18
|
| Entrez Gene |
29074
|
| Alt Symbol |
HSPC071, L18mt, MRP-L18
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
mitochondrial ribosomal protein L18
|
| Other Description |
39S ribosomal protein L18, mitochondrial
|
| Swissprots |
Q9NZW8 Q5TAP9 Q9H0U6
|
| Accessions |
EAW47614 EAW47615 Q9H0U6 AF161556 AAF29043 AK311391 AL136633 CAB66568 AM393775 CAL38650 BC001623 AAH01623 BU932963 CB529016 CR533491 CAG38522 XM_006715466 XP_006715529 NM_014161 NP_054880
|
| Function |
Together with thiosulfate sulfurtransferase (TST), acts as a mitochondrial import factor for the cytosolic 5S rRNA. The precursor form shows RNA chaperone activity; is able to fold the 5S rRNA into an import-competent conformation that is recognized by rhodanese (TST). Both the cytoplasmic and mitochondrial forms are able to bind to the helix IV-loop D in the gamma domain of the 5S rRNA. {ECO:0000269|PubMed:21685364}.
|
| Subcellular Location |
Mitochondrion.
|
| Top Pathways |
Ribosome
|