GGCX

Gene Symbol	GGCX
Entrez Gene	2677
Alt Symbol	VKCFD1
Species	Human
Gene Type	protein-coding
Description	gamma-glutamyl carboxylase
Other Description	peptidyl-glutamate 4-carboxylase|vitamin K-dependent gamma-carboxylase
Swissprots	Q6GU45 B4DMC5 P38435 E9PEE1 Q14415
Accessions	AAB39832 AAF64245 AAY24340 ABV02114 EAW99509 EAW99510 P38435 AK054569 AK130139 AK222827 BAD96547 AK225663 AK297397 BAG59837 AK298982 BAG61076 AK310483 AK313126 BAG35946 BC004422 BC013979 AAH13979 BM974022 DC296316 DQ892948 ABM83874 DQ896196 ABM87195 EU847509 ACF70731 L17128 AAA91834 M81592 AAA58643 XM_005264259 XP_005264316 XM_011532764 XP_011531066 XM_011532765 XP_011531067 XR_939677 NM_000821 NP_000812 NM_001142269 NP_001135741
Function	Mediates the vitamin K-dependent carboxylation of glutamate residues to calcium-binding gamma-carboxyglutamate (Gla) residues with the concomitant conversion of the reduced hydroquinone form of vitamin K to vitamin K epoxide. {ECO:0000269|PubMed:17073445}.
Subcellular Location	Endoplasmic reticulum membrane {ECO:0000269|PubMed:10910912}; Multi-pass membrane protein {ECO:0000269|PubMed:10910912}.
Top Pathways	Ubiquinone and other terpenoid-quinone biosynthesis

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

GGCX CRISPR/Cas9 KO Plasmid (h) - sc-407037 from Santa Cruz Biotechnology Category CRISPR Prices $345.00 Sizes 20 µg Species Reactivities Human

GGCX HDR Plasmid (h) - sc-407037-HDR from Santa Cruz Biotechnology Prices $345.00 Sizes 20 µg Species Reactivities Human

GGCX Double Nickase Plasmid (h) - sc-407037-NIC from Santa Cruz Biotechnology Prices $345.00 Sizes 20 µg Species Reactivities Human

GGCX Double Nickase Plasmid (h2) - sc-407037-NIC-2 from Santa Cruz Biotechnology Prices $345.00 Sizes 20 µg Species Reactivities Human

GGCX CRISPR Activation Plasmid (h) - sc-407037-ACT from Santa Cruz Biotechnology Category CRISPR Prices $345.00 Sizes 20 µg Species Reactivities Human

GGCX CRISPR Activation Plasmid (h2) - sc-407037-ACT-2 from Santa Cruz Biotechnology Category CRISPR Prices $345.00 Sizes 20 µg Species Reactivities Human

GGCX Lentiviral Activation Particles (h) - sc-407037-LAC from Santa Cruz Biotechnology Prices $345.00 Sizes 20 µg Species Reactivities Human

GGCX Lentiviral Activation Particles (h2) - sc-407037-LAC-2 from Santa Cruz Biotechnology Prices $345.00 Sizes 20 µg Species Reactivities Human

GGCX siRNA (h) - sc-75125 from Santa Cruz Biotechnology Category siRNA Prices $258.00 Sizes 10 µm Species Reactivities Human

GGCX shRNA Plasmid (h) - sc-75125-SH from Santa Cruz Biotechnology Category siRNA Prices $258.00 Sizes 10 µm Species Reactivities Human

GGCX shRNA (h) Lentiviral Particles - sc-75125-V from Santa Cruz Biotechnology Category siRNA Prices $258.00 Sizes 10 µm Species Reactivities Human

GGCX RNAi - H00002677-R01 from Novus Biologicals Category siRNA Prices $399.00 Sizes 20 nmol Species Reactivities Human

MISSION® esiRNA - EHU139211 from Sigma-Aldrich Category siRNA Prices $140.00, $250.00 Sizes 20 µg, 50 µg

CompoZr® Knockout ZFN Kit - CKOZFN9256 from Sigma-Aldrich Category ZFN Kit Prices $4,999.00 Sizes 1 kt

CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND9256 from Sigma-Aldrich Category ZFN Kit Prices $3,999.00 Sizes 1 kt

MISSION® 3′UTR Lenti GoClone™ - HUTR07370 from Sigma-Aldrich Category miRNA Prices $350.00 Sizes hutr07370

GGCX siRNA (Human) - CRH1786 from Cohesion Biosciences Category siRNA Prices $340.00, $510.00 Sizes 15 nmol, 30 nmol Species Reactivities Human

GGCX - MBS8219771 from MyBioSource Prices $365.00, $515.00 Sizes 15 nmol, 30 nmol Species Reactivities Human

GGCX CRISPR/Cas9 KO Plasmid (h2) - sc-407037-KO-2 from Santa Cruz Biotechnology Category CRISPR Prices $345.00 Sizes 20 µg Species Reactivities Human

GGCX HDR Plasmid (h2) - sc-407037-HDR-2 from Santa Cruz Biotechnology Prices $345.00 Sizes 20 µg Species Reactivities Human

Human GGCX siRNA - orb262288 from Biorbyt Category siRNA Prices $485.00, $629.00 Sizes 15 nmol, 30 nmol Species Reactivities Human

GGCX shRNA Plasmid (Human) - CHH1786 from Cohesion Biosciences Category siRNA Prices $500.00, $750.00 Sizes 150 µg, 300 µg Species Reactivities Human

GGCX miRNA 3'UTR clone - MiUTR3H-00852 from Creative biogene Species Reactivities Human

GGCX miRNA 3'UTR clone - MiUTR3H-00853 from Creative biogene Species Reactivities Human

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