| Gene Symbol |
UHMK1
|
| Entrez Gene |
127933
|
| Alt Symbol |
KIS, KIST, P-CIP2
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
U2AF homology motif (UHM) kinase 1
|
| Other Description |
KIS protein kinase|PAM COOH-terminal interactor protein 2|kinase interacting with leukemia-associated gene (stathmin)|serine/threonine-protein kinase Kist
|
| Swissprots |
G3V1M1 A8K8K4 Q96C22 Q8TAS1
|
| Accessions |
CAK32272 EAW90706 EAW90707 EAW90708 EAW90709 Q8TAS1 AB384827 BAG10683 AJ536197 CAD60192 AK026668 AK058195 AK292369 BAF85058 AL137257 AL834136 CAI46199 BC001977 BC014917 AAH14917 BC026046 AAH26046 BC043436 XR_921745 NM_001184763 NP_001171692 NM_144624 NP_653225 NM_175866 NP_787062
|
| Function |
Upon serum stimulation, phosphorylates CDKN1B/p27Kip1, thus controlling CDKN1B subcellular location and cell cycle progression in G1 phase. May be involved in trafficking and/or processing of RNA (By similarity). {ECO:0000250}.
|
| Subcellular Location |
Nucleus {ECO:0000269|PubMed:23419774}.
|
| Tissue Specificity |
Widely expressed, with highest levels in skeletal muscle, kidney, placenta and peripheral blood leukocytes. {ECO:0000269|PubMed:12093740}.
|
![Western Blot: KIST Overexpression Lysate (Adult Normal) [NBL1-17602] Left-Empty vector transfected control cell lysate (HEK293 cell lysate); Right -Over-expression Lysate for KIST.](http://www.bioprodhub.com/system/product_images/cel_products/5/sub_2/7879_KIST%2520Overexpression%2520Lysate%2520(Adult%2520Normal)-Western%2520Blot-NBL1-17602-img0002.jpg)