Gene Symbol | UHMK1 |
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Entrez Gene | 127933 |
Alt Symbol | KIS, KIST, P-CIP2 |
Species | Human |
Gene Type | protein-coding |
Description | U2AF homology motif (UHM) kinase 1 |
Other Description | KIS protein kinase|PAM COOH-terminal interactor protein 2|kinase interacting with leukemia-associated gene (stathmin)|serine/threonine-protein kinase Kist |
Swissprots | G3V1M1 A8K8K4 Q96C22 Q8TAS1 |
Accessions | CAK32272 EAW90706 EAW90707 EAW90708 EAW90709 Q8TAS1 AB384827 BAG10683 AJ536197 CAD60192 AK026668 AK058195 AK292369 BAF85058 AL137257 AL834136 CAI46199 BC001977 BC014917 AAH14917 BC026046 AAH26046 BC043436 XR_921745 NM_001184763 NP_001171692 NM_144624 NP_653225 NM_175866 NP_787062 |
Function | Upon serum stimulation, phosphorylates CDKN1B/p27Kip1, thus controlling CDKN1B subcellular location and cell cycle progression in G1 phase. May be involved in trafficking and/or processing of RNA (By similarity). {ECO:0000250}. |
Subcellular Location | Nucleus {ECO:0000269|PubMed:23419774}. |
Tissue Specificity | Widely expressed, with highest levels in skeletal muscle, kidney, placenta and peripheral blood leukocytes. {ECO:0000269|PubMed:12093740}. |
UHMK1 CRISPR/Cas9 KO Plasmid (h) - sc-416377 from Santa Cruz Biotechnology
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UHMK1 HDR Plasmid (h) - sc-416377-HDR from Santa Cruz Biotechnology
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UHMK1 Double Nickase Plasmid (h) - sc-416377-NIC from Santa Cruz Biotechnology
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UHMK1 Double Nickase Plasmid (h2) - sc-416377-NIC-2 from Santa Cruz Biotechnology
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UHMK1 CRISPR Activation Plasmid (h) - sc-416377-ACT from Santa Cruz Biotechnology
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UHMK1 CRISPR Activation Plasmid (h2) - sc-416377-ACT-2 from Santa Cruz Biotechnology
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UHMK1 Lentiviral Activation Particles (h) - sc-416377-LAC from Santa Cruz Biotechnology
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UHMK1 Lentiviral Activation Particles (h2) - sc-416377-LAC-2 from Santa Cruz Biotechnology
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UHMK1 siRNA (h) - sc-78640 from Santa Cruz Biotechnology
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UHMK1 shRNA Plasmid (h) - sc-78640-SH from Santa Cruz Biotechnology
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UHMK1 shRNA (h) Lentiviral Particles - sc-78640-V from Santa Cruz Biotechnology
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KIST RNAi - H00127933-R02 from Novus Biologicals
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MISSION® esiRNA - EHU145951 from Sigma-Aldrich
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MISSION® siRNA - SIHK2416 from Sigma-Aldrich
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MISSION® siRNA - SIHK2417 from Sigma-Aldrich
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MISSION® siRNA - SIHK2415 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN22477 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND22477 from Sigma-Aldrich
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MISSION® 3′UTR Lenti GoClone™ - HUTR09802 from Sigma-Aldrich
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UHMK1 siRNA (Human) - CRJ4937 from Cohesion Biosciences
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UHMK1 - MBS8229417 from MyBioSource
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shRNA set against Human UHMK1 (NM_175866.4) - SHH440288 from Creative biogene
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KIS siRNA - orb219206 from Biorbyt
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Human UHMK1 siRNA - orb275438 from Biorbyt
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UHMK1 shRNA Plasmid (Human) - CHJ4937 from Cohesion Biosciences
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