Gene Symbol | NSUN4 |
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Entrez Gene | 387338 |
Alt Symbol | SHTAP |
Species | Human |
Gene Type | protein-coding |
Description | NOP2/Sun domain family, member 4 |
Other Description | 5-methylcytosine rRNA methyltransferase NSUN4|NOL1/NOP2/Sun domain family member 4|putative methyltransferase NSUN4|sperm head and tail associated protein |
Swissprots | B3KQ50 Q5TDF7 Q9HAJ8 Q96AN8 A8K6S6 Q96CB9 B4DHA4 |
Accessions | EAX06917 EAX06920 Q96CB9 AK021577 BAB13847 AK057420 BAG51912 AK097524 BAG53482 AK128066 BAC87258 AK291741 BAF84430 AK292353 BAF85042 AK295003 BAG58065 AK311009 BC014441 AAH14441 BC016907 AAH16907 BE542166 BG821302 BM153143 BM665392 BM888153 BM994678 BU536211 BX360729 BX648592 CF593490 DA799314 DA905308 NM_001256127 NP_001243056 NM_001256128 NP_001243057 NM_199044 NP_950245 NR_045789 NR_045790 NR_045791 |
Function | Involved in mitochondrial ribosome assembly. 5- methylcytosine rRNA methyltransferase that probably is involved in mitochondrial ribosome small subunit (SSU) maturation by methylation of mitochondrial 12S rRNA; the function is independent of MTERFD2/MTERF4 and assembled mitochondrial ribosome large subunit (LSU). Targeted to LSU by MTERFD2/MTERF4 and probably is involved in a final step in ribosome biogenesis to ensure that SSU and LSU are assembled. In vitro can methylate 16S rRNA of the LSU; the methylation is enhanced by MTERFD/MTERF4. {ECO:0000269|PubMed:21531335, ECO:0000269|PubMed:23022348}. |
Subcellular Location | Mitochondrion {ECO:0000269|PubMed:21531335, ECO:0000269|PubMed:22949673, ECO:0000269|PubMed:23022348}. |
Human NSUN4 full length protein - ab166399 from Abcam
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NSUN4 Antibody Blocking Peptide - LS-E17788 from LifeSpan Bioscience
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NSUN4 Recombinant Protein - H00387338-P01 from Novus Biologicals
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NSUN4-Antibody-C-term-Blocking-peptide - BP11159b from Abgent, a WuXi AppTec company
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NSUN4 Blocking Peptide - 33R-7616 from Fitzgerald
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NSUN4 - H00387338-P01 from Acris Antibodies
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NSUN4 fusion protein - Ag9417 from Proteintech Group
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NSUN4 fusion protein - ag9402 from Proteintech Group
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Recombinant Human NSUN4, His-tagged - NSUN4-1377H from Creative Biomart
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Recombinant Human NSUN4 - NSUN4-1659H from Creative Biomart
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Recombinant Human Putative methyltransferase NSUN4(NSUN4) - CSB-YP850270HU CSB-EP850270HU CSB-BP850270HU CSB-MP850270HU from Cusabio
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NSUN4 Recombinant Protein Antigen - NBP1-82734PEP from Novus Biologicals
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NSUN4 Recombinant Protein Antigen - NBP1-82733PEP from Novus Biologicals
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NSUN4 Peptide, Human - M34GP10654H from Creative Peptides
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Putative methyltransferase NSUN4 (NSUN4), Recombinant Protein - MBS1280533 from MyBioSource
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