| Gene Symbol |
TRMT112
|
| Entrez Gene |
51504
|
| Alt Symbol |
HSPC152, HSPC170, TRM112, TRMT11-2
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
tRNA methyltransferase 11-2 homolog (S. cerevisiae)
|
| Other Description |
TRM112-like protein|multifunctional methyltransferase subunit TRM112-like protein|tRNA methyltransferase 112 homolog
|
| Swissprots |
Q8N2Z4 B2R539 Q9UI30 J3KNG5 Q3MHC7
|
| Accessions |
CAM55961 EAW74251 EAW74252 EAW74253 Q9UI30 AF110774 AAF14857 AF161501 AAF29116 AF229068 AAF82266 AK312050 BAG34986 BC017172 AAH17172 BC029482 AAH29482 BC105294 AAI05295 BE791577 BG533234 CB054126 CN362692 DQ892261 ABM83187 DQ895463 ABM86389 NM_001286082 NP_001273011 NM_001286084 NP_001273013 NM_016404 NP_057488
|
| Function |
Participates both in methylation of protein and tRNA species. The heterodimer with HEMK2/N6AMT1 catalyzes N5- methylation of ETF1 on 'Gln-185', using S-adenosyl L-methionine as methyl donor. The heterodimer with ALKBH8 catalyzes the methylation of 5-carboxymethyl uridine to 5-methylcarboxymethyl uridine at the wobble position of the anticodon loop in target tRNA species. {ECO:0000269|PubMed:18539146}.
|