Gene Symbol | TRMT112 |
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Entrez Gene | 51504 |
Alt Symbol | HSPC152, HSPC170, TRM112, TRMT11-2 |
Species | Human |
Gene Type | protein-coding |
Description | tRNA methyltransferase 11-2 homolog (S. cerevisiae) |
Other Description | TRM112-like protein|multifunctional methyltransferase subunit TRM112-like protein|tRNA methyltransferase 112 homolog |
Swissprots | Q8N2Z4 B2R539 Q9UI30 J3KNG5 Q3MHC7 |
Accessions | CAM55961 EAW74251 EAW74252 EAW74253 Q9UI30 AF110774 AAF14857 AF161501 AAF29116 AF229068 AAF82266 AK312050 BAG34986 BC017172 AAH17172 BC029482 AAH29482 BC105294 AAI05295 BE791577 BG533234 CB054126 CN362692 DQ892261 ABM83187 DQ895463 ABM86389 NM_001286082 NP_001273011 NM_001286084 NP_001273013 NM_016404 NP_057488 |
Function | Participates both in methylation of protein and tRNA species. The heterodimer with HEMK2/N6AMT1 catalyzes N5- methylation of ETF1 on 'Gln-185', using S-adenosyl L-methionine as methyl donor. The heterodimer with ALKBH8 catalyzes the methylation of 5-carboxymethyl uridine to 5-methylcarboxymethyl uridine at the wobble position of the anticodon loop in target tRNA species. {ECO:0000269|PubMed:18539146}. |
TRMT112 CRISPR/Cas9 KO Plasmid (h) - sc-412208 from Santa Cruz Biotechnology
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TRMT112 HDR Plasmid (h) - sc-412208-HDR from Santa Cruz Biotechnology
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TRMT112 Double Nickase Plasmid (h) - sc-412208-NIC from Santa Cruz Biotechnology
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TRMT112 Double Nickase Plasmid (h2) - sc-412208-NIC-2 from Santa Cruz Biotechnology
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TRMT112 CRISPR Activation Plasmid (h) - sc-412208-ACT from Santa Cruz Biotechnology
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TRMT112 CRISPR Activation Plasmid (h2) - sc-412208-ACT-2 from Santa Cruz Biotechnology
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TRMT112 Lentiviral Activation Particles (h) - sc-412208-LAC from Santa Cruz Biotechnology
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TRMT112 Lentiviral Activation Particles (h2) - sc-412208-LAC-2 from Santa Cruz Biotechnology
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TRMT112 siRNA (h) - sc-96298 from Santa Cruz Biotechnology
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TRMT112 shRNA Plasmid (h) - sc-96298-SH from Santa Cruz Biotechnology
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TRMT112 shRNA (h) Lentiviral Particles - sc-96298-V from Santa Cruz Biotechnology
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HPSC152 RNAi - H00051504-R01 from Novus Biologicals
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MISSION® esiRNA - EHU041191 from Sigma-Aldrich
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MISSION® esiRNA - EHU101821 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN22036 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND22036 from Sigma-Aldrich
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MISSION® 3′UTR Lenti GoClone™ - HUTR00201 from Sigma-Aldrich
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TRMT112 siRNA (Human) - CRH9798 from Cohesion Biosciences
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TRMT112 - MBS829074 from MyBioSource
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shRNA set against Human TRMT112 (NM_016404.1) - SHH435280 from Creative biogene
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shRNA set against Human HSPC152(NM_016404.1) - SHH134867 from Creative biogene
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Human TRMT112 siRNA - orb270300 from Biorbyt
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TRMT112 shRNA Plasmid (Human) - CHH9798 from Cohesion Biosciences
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TRMT112 miRNA 3'UTR clone - MiUTR1H-04743 from Creative biogene
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