Gene Symbol |
SNX16
|
Entrez Gene |
64089
|
Alt Symbol |
-
|
Species |
Human
|
Gene Type |
protein-coding
|
Description |
sorting nexin 16
|
Other Description |
sorting nexin-16
|
Swissprots |
P57768 Q658L0 Q8N4U3 A8K4D8
|
Accessions |
EAW87108 EAW87109 P57768 AF305779 AAG25676 AK290903 BAF83592 AL833763 CAH56235 BC033630 AAH33630 BG700892 BG739930 CB962009 DA307370 HQ448008 ADQ32489 XM_005251282 XP_005251339 XM_005251283 XP_005251340 XM_005251284 XP_005251341 XM_011517573 XP_011515875 XM_011517574 XP_011515876 NM_022133 NP_071416 NM_152836 NP_690049 NM_152837 NP_690050
|
Function |
May be involved in several stages of intracellular trafficking. Plays a role in protein transport from early to late endosomes. Plays a role in protein transport to the lysosome. Promotes degradation of EGFR after EGF signaling. Plays a role in intracellular transport of vesicular stomatitis virus nucleocapsids from the endosome to the cytoplasm. {ECO:0000269|PubMed:12813048, ECO:0000269|PubMed:15951806}.
|
Subcellular Location |
Early endosome membrane; Peripheral membrane protein; Cytoplasmic side. Late endosome membrane; Peripheral membrane protein; Cytoplasmic side. Cytoplasm {ECO:0000250}. Lysosome {ECO:0000250}.
|
Tissue Specificity |
Detected in placenta, lung, liver,heart and pancreas. {ECO:0000269|PubMed:12813048}.
|