Gene Symbol | SNX16 |
---|---|
Entrez Gene | 64089 |
Alt Symbol | - |
Species | Human |
Gene Type | protein-coding |
Description | sorting nexin 16 |
Other Description | sorting nexin-16 |
Swissprots | P57768 Q658L0 Q8N4U3 A8K4D8 |
Accessions | EAW87108 EAW87109 P57768 AF305779 AAG25676 AK290903 BAF83592 AL833763 CAH56235 BC033630 AAH33630 BG700892 BG739930 CB962009 DA307370 HQ448008 ADQ32489 XM_005251282 XP_005251339 XM_005251283 XP_005251340 XM_005251284 XP_005251341 XM_011517573 XP_011515875 XM_011517574 XP_011515876 NM_022133 NP_071416 NM_152836 NP_690049 NM_152837 NP_690050 |
Function | May be involved in several stages of intracellular trafficking. Plays a role in protein transport from early to late endosomes. Plays a role in protein transport to the lysosome. Promotes degradation of EGFR after EGF signaling. Plays a role in intracellular transport of vesicular stomatitis virus nucleocapsids from the endosome to the cytoplasm. {ECO:0000269|PubMed:12813048, ECO:0000269|PubMed:15951806}. |
Subcellular Location | Early endosome membrane; Peripheral membrane protein; Cytoplasmic side. Late endosome membrane; Peripheral membrane protein; Cytoplasmic side. Cytoplasm {ECO:0000250}. Lysosome {ECO:0000250}. |
Tissue Specificity | Detected in placenta, lung, liver,heart and pancreas. {ECO:0000269|PubMed:12813048}. |