| Gene Symbol |
MTMR6
|
| Entrez Gene |
9107
|
| Alt Symbol |
-
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
myotubularin related protein 6
|
| Other Description |
myotubularin-related protein 6
|
| Swissprots |
B2RBB5 B3KSB4 Q9Y217 Q96P80 Q86TB7 Q5JRG6 Q86YH4
|
| Accessions |
EAX08367 Q9Y217 AF072928 AAC78841 AF406619 AAL01037 AK025507 AK093237 AK094082 AK314587 BAG37162 AL044815 AL832017 CAD89918 AM392681 CAL37559 AM392837 CAL37715 BC031834 AAH31834 BC035436 BC040012 AAH40012 BU177677 EF491793 U47635 AAB18856 XM_011535306 XP_011533608 XM_011535307 XP_011533609 XM_011535308 XP_011533610 NM_004685 NP_004676
|
| Function |
Phosphatase that acts on lipids with a phosphoinositol headgroup. Acts as a negative regulator of KCNN4/KCa3.1 channel activity in CD4+ T-cells possibly by decreasing intracellular levels of phosphatidylinositol 3 phosphatase. Negatively regulates proliferation of reactivated CD4+ T-cells. {ECO:0000269|PubMed:15831468, ECO:0000269|PubMed:16847315}.
|
| Subcellular Location |
Nucleus envelope {ECO:0000269|PubMed:16787938}.
|
| Tissue Specificity |
Expressed in CD4+ T-cells. {ECO:0000269|PubMed:16847315}.
|