Gene Symbol | RHOT2 |
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Entrez Gene | 89941 |
Alt Symbol | ARHT2, C16orf39, MIRO-2, MIRO2, RASL |
Species | Human |
Gene Type | protein-coding |
Description | ras homolog family member T2 |
Other Description | mitochondrial Rho (MIRO) GTPase 2|mitochondrial Rho GTPase 2|ras homolog gene family, member T2 |
Swissprots | Q9H7M8 A2IDC2 Q9BT60 Q8NF53 Q8IXI1 Q96C13 Q96S17 |
Accessions | AAK61240 CBJ05785 CBJ21237 EAW85763 EAW85764 EAW85765 EAW85766 EAW85767 EAW85768 Q8IXI1 AJ517413 CAD56957 AK024450 BAB15740 AK090426 BAC03407 AK308984 AL834163 AY207375 AAP46090 BC004327 AAH04327 BC014942 AAH14942 DB465261 XM_005255660 XP_005255717 XM_005255661 XP_005255718 XM_005255662 XP_005255719 XM_005255663 XP_005255720 XM_005255664 XP_005255721 XM_006720970 XP_006721033 XM_006720971 XP_006721034 XM_006720973 XP_006721036 XR_932964 NM_138769 NP_620124 |
Function | Mitochondrial GTPase involved in mitochondrial trafficking. Probably involved in control of anterograde transport of mitochondria and their subcellular distribution (By similarity). {ECO:0000250}. |
Subcellular Location | Mitochondrion outer membrane {ECO:0000269|PubMed:12482879, ECO:0000269|PubMed:19528298}; Single-pass type IV membrane protein {ECO:0000269|PubMed:12482879, ECO:0000269|PubMed:19528298}. Note=Colocalizes with MGARP and RHOT2 at the mitochondria. |
Tissue Specificity | Ubiquitously expressed. Highly expressed in heart, liver, skeletal muscle, kidney and pancreas. {ECO:0000269|PubMed:12482879, ECO:0000269|PubMed:15218247}. |
Rho T2 CRISPR/Cas9 KO Plasmid (h) - sc-406496 from Santa Cruz Biotechnology
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Rho T2 HDR Plasmid (h) - sc-406496-HDR from Santa Cruz Biotechnology
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Rho T2 Double Nickase Plasmid (h) - sc-406496-NIC from Santa Cruz Biotechnology
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Rho T2 Double Nickase Plasmid (h2) - sc-406496-NIC-2 from Santa Cruz Biotechnology
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Rho T2 CRISPR Activation Plasmid (h) - sc-406496-ACT from Santa Cruz Biotechnology
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Rho T2 CRISPR Activation Plasmid (h2) - sc-406496-ACT-2 from Santa Cruz Biotechnology
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Rho T2 Lentiviral Activation Particles (h) - sc-406496-LAC from Santa Cruz Biotechnology
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Rho T2 Lentiviral Activation Particles (h2) - sc-406496-LAC-2 from Santa Cruz Biotechnology
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Rho T2 siRNA (h) - sc-93029 from Santa Cruz Biotechnology
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Rho T2 shRNA Plasmid (h) - sc-93029-SH from Santa Cruz Biotechnology
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Rho T2 shRNA (h) Lentiviral Particles - sc-93029-V from Santa Cruz Biotechnology
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RHOT2 RNAi - H00089941-R01 from Novus Biologicals
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CompoZr® Knockout ZFN Kit - CKOZFN18262 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND18262 from Sigma-Aldrich
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MISSION® 3′UTR Lenti GoClone™ - HUTR04495 from Sigma-Aldrich
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RHOT2 siRNA (Human) - CRJ3889 from Cohesion Biosciences
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RHOT2 - MBS8233808 from MyBioSource
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shRNA set against Human RHOT2 (NM_138769.2) - SHH395412 from Creative biogene
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RHOT2 shRNA Plasmid (Human) - CHJ3889 from Cohesion Biosciences
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RHOT2 miRNA 3'UTR clone - MiUTR3H-13064 from Creative biogene
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