RABGEF1

Gene Symbol RABGEF1
Entrez Gene 27342
Alt Symbol RABEX5, RAP1, rabex-5
Species Human
Gene Type protein-coding
Description RAB guanine nucleotide exchange factor (GEF) 1
Other Description rab5 GDP/GTP exchange factor|rabaptin-5-associated exchange factor for Rab5
Swissprots Q3HKR3 B4DZM7 Q3HKR2 Q53FG0 Q9UJ41
Accessions AAQ93362 EAX07913 EAX07914 EAX07915 EAX07916 Q9UJ41 AA643570 AI017520 AI061350 AJ250042 CAB57359 AK001702 BAG50963 AK056864 AK223329 BAD97049 AK290678 BAF83367 AK303006 BAG64139 AW196783 BC015330 AAH15330 BF035201 BM310029 BT007107 AAP35771 CD366530 CN305879 DA196847 DB445225 DC402344 DQ230533 ABA64473 DQ230534 ABA64474 DQ230535 ABA64475 HY010703 NM_001287060 NP_001273989 NM_001287061 NP_001273990 NM_001287062 NP_001273991 NM_014504 NP_055319 NR_104676
Function Rab effector protein acting as linker between gamma- adaptin, RAB4A or RAB5A. Involved in endocytic membrane fusion and membrane trafficking of recycling endosomes. Stimulates nucleotide exchange on RAB5A. Can act as a ubiquitin ligase (By similarity). {ECO:0000250}.
Subcellular Location Cytoplasm {ECO:0000269|PubMed:12505986}. Early endosome {ECO:0000269|PubMed:12505986}. Recycling endosome {ECO:0000269|PubMed:12505986}.

Rabex-5 (D21F12) Rabbit mAb - 7622 from Cell Signaling Technology

Prices $246.00
Sizes 100 µl (10 western blots)
Host Rabbit
Clonality Monoclonal
Clone D21F12
Western blot analysis of extracts from SH-SY5Y cells, transfected with 100 nM SignalSilence® Control siRNA (Unconjugated) #6568 (-) or SignalSilence® Rabex-5 siRNA I (+), using Rabex-5 (D21F12) Rabbit mAb #7622 (upper) or α-Tubulin (11H10) Rabbit mAb #2125 (lower). The Rabex-5 (D21F12) Rabbit mAb confirms silencing of Rabex-5 expression, while the α-Tubulin (11H10) Rabbit mAb is used as a loading control.

Rabex-5 (H-288) - sc-68344 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Rabbit
Clonality Polyclonal
Rabex-5 (H-288): sc-68344. Western blot analysis of Rabex-5 expression in non-transfected: sc-117752 (A) and human Rabex-5 transfected: sc-113412 (B) 293T whole cell lysates.

Rabex-5 (C-4) - sc-166049 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
Rabex-5 (C-4): sc-166049. Western blot analysis of Rabex-5 expression in non-transfected: sc-117752 (A) and human Rabex-5 transfected: sc-113412 (B) 293T whole cell lysates.

Rabex-5 (D-8) - sc-166050 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
Rabex-5 (D-8): sc-166050. Western blot analysis of Rabex-5 expression in non-transfected: sc-117752 (A) and human Rabex-5 transfected: sc-113412 (B) 293T whole cell lysates.

Rabex-5 (A-7) - sc-166611 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
Rabex-5 (A-7): sc-166611. Western blot analysis of Rabex-5 expression in MIA PaCa-2 (A), NIH/3T3 (B) and KNRK (C) whole cell lysates.

Rabex-5 (D-11) - sc-166496 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
Rabex-5 (D-11): sc-166496. Western blot analysis of Rabex-5 expression in non-transfected: sc-117752 (A) and human Rabex-5 transfected: sc-113412 (B) 293T whole cell lysates.

Rabex-5 (S-16) - sc-55275 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal

Rabex-5 (Q-15) - sc-55274 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal

Anti-Rabex5 antibody - ab113480 from Abcam

Prices $370.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
Immunofluorescence of Rabex5 in mouse brain tissue with ab113480 at 20 ug/mL.

Anti-Rabex5 antibody - ab200231 from Abcam

Prices $359.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal
Anti-Rabex5 antibody (ab200231) at 1/500 dilution + Human liver lysate

Anti-Rabex5 antibody - ab103520 from Abcam

Prices $370.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) analysis of human lung carcinoma tissue labelling Rabex5 with ab103520 at 1/1000 (1µg/ml). Detection: DAB.

Anti-Rabex5 antibody - ab69437 from Abcam

Prices $370.00
Sizes 50 µg
Host Mouse
Clonality Polyclonal
Anti-Rabex5 antibody (ab69437) at 1/500 dilution + human liver tissue lysate at 25 µgSecondaryGoat Anti-Mouse IgG (H&L)-HRP at 1/2500 dilution

Anti-RABGEF1 Antibody (aa175-225) - LS-C289631 from LifeSpan Bioscience

Prices $375.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Detection of Human RABGEF1 by Immunohistochemistry. Sample: FFPE section of human lung carcinoma. Antibody: Affinity purified rabbit anti-RABGEF1 used at a dilution of 1:1000 (1 ug/ml). Detection: DAB.

Anti-RABGEF1 Antibody (Internal) - LS-C144342 from LifeSpan Bioscience

Prices $345.00, $1,035.00
Sizes 100 µg, 500 µg
Host Rabbit
Clonality Polyclonal
Immunofluorescence of RABEX5 in mouse brain tissue with RABEX5 antibody at 20 ug/ml.

Anti-RABGEF1 Antibody (aa475-525) - LS-C289630 from LifeSpan Bioscience

Prices $375.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Detection of Human RABGEF1 by Immunohistochemistry. Sample: FFPE section of human lung carcinoma. Antibody: Affinity purified rabbit anti-RABGEF1 used at a dilution of 1:1000 (1 ug/ml). Detection: DAB.

Anti-RABGEF1 Antibody (N-Terminus) - LS-C111598 from LifeSpan Bioscience

Prices $365.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
RABGEF1 antibody LS-C111598 Western blot of HT1080 cell lysate.

Anti-RABGEF1 Antibody (C-Terminus) - LS-C305967 from LifeSpan Bioscience

Prices $445.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
Western blot of RABGEF1 antibody LS-X234981.

Rabex5 Antibody - NBP1-76548 from Novus Biologicals

Prices $329.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
Western Blot: Rabex5 Antibody [NBP1-76548] - Analysis in human liver tissue lysate with antibody at (A) 1 and (B) 2 ug/mL.

Rabex5 Antibody - NBP1-49938 from Novus Biologicals

Prices $359.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

Rabex5 Antibody - H00027342-B01P from Novus Biologicals

Prices $359.00
Sizes 50 µg
Host Mouse
Clonality Polyclonal

Rabex5 Antibody - H00027342-B01 from Novus Biologicals

Prices $349.00
Sizes 50 µl
Host Mouse
Clonality Polyclonal
Western Blot: Rabex5 Antibody [H00027342-B01] - RABGEF1 MaxPab polyclonal antibody (B01), Lot # 08080 WULz. Western Blot analysis of RABGEF1 expression in human liver.

RABX5 Polyclonal Antibody - bs-6916R from Bioss

Prices $269.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

Anti-RABGEF1 antibody produced in mouse - SAB1407359 from Sigma-Aldrich

Prices $347.00
Sizes 50 µg
Host Mouse
Clonality Polyclonal
<B>Immunoblotting</B><BR/>Anti-RABGEF1: <B>Cat. No. SAB1407359</B>: Antibody concentration: 1-5 μg/mL. Specific band of ~79.4 kDa using human liver lysate.

Anti-Rabex-5 (N-terminal) antibody produced in rabbit - R5405 from Sigma-Aldrich

Prices $340.00, $440.00
Sizes 100 µl, 200 µl
Host Rabbit
Clonality Polyclonal
<B>Immunofluorescence</B><BR/>NRK cells were fixed and permeabilized with 4% paraformaldehyde followed by 0.4% saponin. Fixed cells were stained with 10 μg/mL Rabbit Anti-Rabex-5 (N-terminal) (<B>Cat. No. R5405</B>). The antibody was developed using Goat Anti-Rabbit IgG, Cy3 conjugate.

Anti-RABEX5 antibody produced in rabbit - SAB3500995 from Sigma-Aldrich

Prices $341.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
<B>Immunoblotting</B><BR/>RABEX5 Antibody: <B>Cat. No. SAB3500995</B>: Western blot analysis of RABEX5 in Rat brain tissue lysate with RABEX5 antibody at 1 μg/mL.
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