Gene Symbol | RABGEF1 |
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Entrez Gene | 27342 |
Alt Symbol | RABEX5, RAP1, rabex-5 |
Species | Human |
Gene Type | protein-coding |
Description | RAB guanine nucleotide exchange factor (GEF) 1 |
Other Description | rab5 GDP/GTP exchange factor|rabaptin-5-associated exchange factor for Rab5 |
Swissprots | Q3HKR3 B4DZM7 Q3HKR2 Q53FG0 Q9UJ41 |
Accessions | AAQ93362 EAX07913 EAX07914 EAX07915 EAX07916 Q9UJ41 AA643570 AI017520 AI061350 AJ250042 CAB57359 AK001702 BAG50963 AK056864 AK223329 BAD97049 AK290678 BAF83367 AK303006 BAG64139 AW196783 BC015330 AAH15330 BF035201 BM310029 BT007107 AAP35771 CD366530 CN305879 DA196847 DB445225 DC402344 DQ230533 ABA64473 DQ230534 ABA64474 DQ230535 ABA64475 HY010703 NM_001287060 NP_001273989 NM_001287061 NP_001273990 NM_001287062 NP_001273991 NM_014504 NP_055319 NR_104676 |
Function | Rab effector protein acting as linker between gamma- adaptin, RAB4A or RAB5A. Involved in endocytic membrane fusion and membrane trafficking of recycling endosomes. Stimulates nucleotide exchange on RAB5A. Can act as a ubiquitin ligase (By similarity). {ECO:0000250}. |
Subcellular Location | Cytoplasm {ECO:0000269|PubMed:12505986}. Early endosome {ECO:0000269|PubMed:12505986}. Recycling endosome {ECO:0000269|PubMed:12505986}. |
Rabex-5 (D21F12) Rabbit mAb - 7622 from Cell Signaling Technology
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Rabex-5 (H-288) - sc-68344 from Santa Cruz Biotechnology
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Rabex-5 (C-4) - sc-166049 from Santa Cruz Biotechnology
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Rabex-5 (D-8) - sc-166050 from Santa Cruz Biotechnology
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Rabex-5 (A-7) - sc-166611 from Santa Cruz Biotechnology
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Rabex-5 (D-11) - sc-166496 from Santa Cruz Biotechnology
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Rabex-5 (S-16) - sc-55275 from Santa Cruz Biotechnology
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Rabex-5 (Q-15) - sc-55274 from Santa Cruz Biotechnology
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Anti-Rabex5 antibody - ab113480 from Abcam
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Anti-Rabex5 antibody - ab200231 from Abcam
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Anti-Rabex5 antibody - ab103520 from Abcam
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Anti-Rabex5 antibody - ab69437 from Abcam
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Anti-RABGEF1 Antibody (aa175-225) - LS-C289631 from LifeSpan Bioscience
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Anti-RABGEF1 Antibody (Internal) - LS-C144342 from LifeSpan Bioscience
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Anti-RABGEF1 Antibody (aa475-525) - LS-C289630 from LifeSpan Bioscience
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Anti-RABGEF1 Antibody (N-Terminus) - LS-C111598 from LifeSpan Bioscience
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Anti-RABGEF1 Antibody (C-Terminus) - LS-C305967 from LifeSpan Bioscience
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Rabex5 Antibody - NBP1-76548 from Novus Biologicals
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Rabex5 Antibody - NBP1-49938 from Novus Biologicals
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Rabex5 Antibody - H00027342-B01P from Novus Biologicals
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Rabex5 Antibody - H00027342-B01 from Novus Biologicals
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RABX5 Polyclonal Antibody - bs-6916R from Bioss
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Anti-RABGEF1 antibody produced in mouse - SAB1407359 from Sigma-Aldrich
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Anti-Rabex-5 (N-terminal) antibody produced in rabbit - R5405 from Sigma-Aldrich
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Anti-RABEX5 antibody produced in rabbit - SAB3500995 from Sigma-Aldrich
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