| Gene Symbol |
ADPRM
|
| Entrez Gene |
56985
|
| Alt Symbol |
C17orf48, MDS006, NBLA03831
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
ADP-ribose/CDP-alcohol diphosphatase, manganese-dependent
|
| Other Description |
ADP-ribose/CDP-alcohol pyrophosphatase|ADPRibase-Mn|CDP-choline phosphohydrolase|manganese-dependent ADP-ribose/CDP-alcohol diphosphatase
|
| Swissprots |
Q9NRU8 Q9BVD4 D3DTS4 A8K9B4 Q3LIE5
|
| Accessions |
EAW89995 EAW89996 Q3LIE5 AB073393 BAE45723 AF168715 AAF87317 AK292629 BAF85318 BC001294 AAH01294 BC070155 AAH70155 DA280275 DA305828 KF880964 AHG56452 XM_005256738 XP_005256795 XR_243561 XR_243562 NM_020233 NP_064618
|
| Function |
Hydrolyzes ADP-ribose, IDP-ribose, CDP-glycerol, CDP- choline and CDP-ethanolamine, but not other non-reducing ADP- sugars or CDP-glucose. May be involved in immune cell signaling as suggested by the second-messenger role of ADP-ribose, which activates TRPM2 as a mediator of oxidative/nitrosative stress (By similarity). {ECO:0000250}.
|
| Top Pathways |
Purine metabolism, Glycerophospholipid metabolism
|