Gene Symbol | ADPRM |
---|---|
Entrez Gene | 56985 |
Alt Symbol | C17orf48, MDS006, NBLA03831 |
Species | Human |
Gene Type | protein-coding |
Description | ADP-ribose/CDP-alcohol diphosphatase, manganese-dependent |
Other Description | ADP-ribose/CDP-alcohol pyrophosphatase|ADPRibase-Mn|CDP-choline phosphohydrolase|manganese-dependent ADP-ribose/CDP-alcohol diphosphatase |
Swissprots | Q9NRU8 Q9BVD4 D3DTS4 A8K9B4 Q3LIE5 |
Accessions | EAW89995 EAW89996 Q3LIE5 AB073393 BAE45723 AF168715 AAF87317 AK292629 BAF85318 BC001294 AAH01294 BC070155 AAH70155 DA280275 DA305828 KF880964 AHG56452 XM_005256738 XP_005256795 XR_243561 XR_243562 NM_020233 NP_064618 |
Function | Hydrolyzes ADP-ribose, IDP-ribose, CDP-glycerol, CDP- choline and CDP-ethanolamine, but not other non-reducing ADP- sugars or CDP-glucose. May be involved in immune cell signaling as suggested by the second-messenger role of ADP-ribose, which activates TRPM2 as a mediator of oxidative/nitrosative stress (By similarity). {ECO:0000250}. |
Top Pathways | Purine metabolism, Glycerophospholipid metabolism |
C17orf48 CRISPR/Cas9 KO Plasmid (h) - sc-412743 from Santa Cruz Biotechnology
|
||||||||
C17orf48 HDR Plasmid (h) - sc-412743-HDR from Santa Cruz Biotechnology
|
||||||||
C17orf48 Double Nickase Plasmid (h) - sc-412743-NIC from Santa Cruz Biotechnology
|
||||||||
C17orf48 Double Nickase Plasmid (h2) - sc-412743-NIC-2 from Santa Cruz Biotechnology
|
||||||||
C17orf48 CRISPR Activation Plasmid (h) - sc-412743-ACT from Santa Cruz Biotechnology
|
||||||||
C17orf48 CRISPR Activation Plasmid (h2) - sc-412743-ACT-2 from Santa Cruz Biotechnology
|
||||||||
C17orf48 Lentiviral Activation Particles (h) - sc-412743-LAC from Santa Cruz Biotechnology
|
||||||||
C17orf48 Lentiviral Activation Particles (h2) - sc-412743-LAC-2 from Santa Cruz Biotechnology
|
||||||||
C17orf48 siRNA (h) - sc-93613 from Santa Cruz Biotechnology
|
||||||||
C17orf48 shRNA Plasmid (h) - sc-93613-SH from Santa Cruz Biotechnology
|
||||||||
C17orf48 shRNA (h) Lentiviral Particles - sc-93613-V from Santa Cruz Biotechnology
|
||||||||
MISSION® esiRNA - EHU034901 from Sigma-Aldrich
|
||||||||
CompoZr® Knockout ZFN Kit - CKOZFN4457 from Sigma-Aldrich
|
||||||||
CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND4457 from Sigma-Aldrich
|
||||||||
ADPRM siRNA (Human) - CRJ1271 from Cohesion Biosciences
|
||||||||
ADPRM - MBS8203332 from MyBioSource
|
||||||||
shRNA set against Human C17orf48 (NM_020233.4) - SHH249839 from Creative biogene
|
||||||||
Human ADPRM siRNA - orb271772 from Biorbyt
|
||||||||
ADPRM shRNA Plasmid (Human) - CHJ1271 from Cohesion Biosciences
|
||||||||
ADPRM miRNA 3'UTR clone - MiUTR1H-01166 from Creative biogene
|