RAB17

Gene Symbol	RAB17
Entrez Gene	64284
Alt Symbol	-
Species	Human
Gene Type	protein-coding
Description	RAB17, member RAS oncogene family
Other Description	ras-related protein Rab-17
Swissprots	Q9H0T7 Q6IA73 Q9H9U9 Q53QV6 Q9BVU1 Q6PJZ0
Accessions	AAY24047 EAW71118 EAW71119 EAW71120 Q9H0T7 AK022600 BAB14121 AK225423 AL136645 CAB66580 AM392800 CAL37678 BC000929 AAH00929 BC007907 AAH07907 BC009827 AAH09827 BC023661 BC050426 AAH50426 BP313619 BX647412 CR457282 CAG33563 CR533454 CAG38485 XM_006712687 XP_006712750 XM_006712688 XP_006712751 XM_006712689 XP_006712752 NM_022449 NP_071894 NR_033308
Function	The small GTPases Rab are key regulators of intracellular membrane trafficking, from the formation of transport vesicles to their fusion with membranes. Rabs cycle between an inactive GDP-bound form and an active GTP-bound form that is able to recruit to membranes different set of downstream effectors directly responsible for vesicle formation, movement, tethering and fusion. That Rab is involved in transcytosis, the directed movement of endocytosed material through the cell and its exocytosis from the plasma membrane at the opposite side. Mainly observed in epithelial cells, transcytosis mediates for instance, the transcellular transport of immunoglobulins from the basolateral surface to the apical surface. Most probably controls membrane trafficking through apical recycling endosomes in a post- endocytic step of transcytosis. Required for melanosome transport and release from melanocytes, it also regulates dendrite and dendritic spine development (By similarity). May also play a role
Subcellular Location	Recycling endosome membrane {ECO:0000250}; Lipid-anchor {ECO:0000250}; Cytoplasmic side {ECO:0000250}. Cell projection, dendrite {ECO:0000250}. Note=May also localize at the basolateral and apical plasma membrane. In neurons, localizes to the cell body and dendritic shaft and spine (By similarity). {ECO:0000250}.
Tissue Specificity	Expressed in melanocytes (at protein level). {ECO:0000269|PubMed:21291502}.

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Active mouse Rab17 full length protein - ab90777 from Abcam Category Protein Prices $239.00 Sizes 50 µg Source E. coli Species Mouse

Active mouse Rab17 full length protein - ab90779 from Abcam Category Protein Prices $243.00 Sizes 50 µg Source E. coli Species Mouse

Human Rab17 full length protein - ab109833 from Abcam Category Protein Source E. coli Species Human

RAB17 Antibody Blocking Peptide - LS-E6097 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

RAB17 Antibody Blocking Peptide - LS-E26603 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

Rab17 Recombinant Protein - H00064284-P01 from Novus Biologicals Category Protein Prices $369.00 Sizes 10 µg Species Human

Recombinant Human Rab17 Protein - NBP1-72354 from Novus Biologicals Category Protein Prices $269.00, $729.00 Sizes 100 µg, 500 µg Source E. coli Species Human

RAB17 Protein (OPPA00145) - OPPA00145 from Aviva Systems Biology Category Protein Prices $100.00 Sizes 5 µg Source Escherichia Coli.

Human RAB17 protein - orb169132 from Biorbyt Category Protein Prices $170.00, $289.00 Sizes 5 μg, 20 μg Source E. coli

Goat anti Rab17 antibody Immunizing peptide - orb54799 from Biorbyt Category Peptide Prices $247.00 Sizes 100 μg Species Human, Mouse, Rat

RAB17 protein (His tag) - 80R-1867 from Fitzgerald Category Protein Prices $255.00 Sizes 100 µg Source E.coli

RAB17 (1-212, His-tag) - AR39048PU-L from Acris Antibodies Category Protein Prices $790.00 Sizes 500 µg Source E. coli Species Human

RAB17 (1-212, His-tag) - AR39048PU-N from Acris Antibodies Category Protein Prices $340.00 Sizes 100 µg Source E. coli Species Human

RAB17 - H00064284-P01-10 from Acris Antibodies Category Protein Prices $380.00 Sizes 10 µg Source in vitro transl. Species Human

RAB17 - H00064284-P01-25 from Acris Antibodies Category Protein Prices $500.00 Sizes 25 µg Source in vitro transl. Species Human

RAB17, Member RAS Oncogene Family, Human Recombinant - 228-13313-1 from RayBiotech Category Protein Prices $118.00 Sizes 1 µg Species Human

Recombinant Human RAB17, Member RAS Oncogene Family - 228-13313-2 from RayBiotech Category Protein Prices $189.00 Sizes 2 µg Source Escherichia Coli. Species Human

Recombinant Human RAB17, Member RAS Oncogene Family - 228-13313-3 from RayBiotech Category Protein Prices $2,880.00 Sizes 3 µg Source Escherichia Coli. Species Human

RAB17, 1-212aa, Human, His tag, E.coli - 11-RAB17 from ARP American Research Products Category Protein Prices $179.00, $369.00, $849.00 Sizes 20 µg, 100 µg, 500 µg Species Human

RAB17 fusion protein - Ag11688 from Proteintech Group Category Protein Prices $199.00 Sizes 50 μg Source E. coli -derived, PET28a Species Human

RAB17 Human - PRPS-881 from NeoScientific Category Protein Prices $65.00, $169.00, $3,510.00 Sizes 5 µg, 20 µg, 1 mg Source Escherichia Coli. Species Human

Recombinant Human RAB17, Member RAS Oncogene Family Protein - BP002330-PRO-874 from Syd Labs Category Protein Prices $160.00, $2,700.00 Sizes 20 µg, 1 mg Source E. coli-derived. Species Human

RAB17, 1-212aa, Recombinant Protein - GWB-P0930G from Genway Biotech Category Protein Prices $300.00, $900.00 Sizes 100 μg, 500 μg Source E.coli Species Human

Recombinant Human RAB17, His-tagged - RAB17-3588H from Creative Biomart Category Protein

Recombinant Human RAB17, His-tagged - RAB17-31274TH from Creative Biomart Category Protein Source E. coli Species Human

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