| Gene Symbol |
ARHGAP27
|
| Entrez Gene |
201176
|
| Alt Symbol |
CAMGAP1, PP905, SH3D20, SH3P20
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
Rho GTPase activating protein 27
|
| Other Description |
CIN85-associated multi-domain-containing Rho GTPase-activating protein 1|SH3 domain containing 20|SH3 domain-containing protein 20|rho GTPase-activating protein 27|rho-type GTPase-activating protein 27
|
| Swissprots |
Q8WY58 C9JTF3 Q494U0 A8K3N5 Q6NWZ8 Q6ZUM4 A4FU35
|
| Accessions |
EAW51527 EAW51528 Q6ZUM4 AF258593 AAG23796 AK092891 AK125535 BAC86196 AK290650 BAF83339 AK300880 BAH13366 BC029634 AAH29634 BC067345 AAH67345 BC101388 AAI01389 BC101389 AAI01390 BC101390 AAI01391 BC101391 AAI01392 BX386761 CD675139 XM_005257128 XP_005257185 XM_005275642 XP_005275699 XM_006721745 XP_006721808 XM_006721747 XP_006721810 XM_006721750 XP_006721813 XM_006725259 XP_006725322 XM_006725261 XP_006725324 XM_006725608 XP_006725671 XM_006725610 XP_006725673 XM_006725613 XP_006725676 XM_006725615 XP_006725678 XM_011524468 XP_011522770 XM_011524469 XP_011522771 XM_011524470 XP_011522772 XM_011524471 XP_011522773 XM_011524472 XP_011522774 XM_011524473 XP_011522775 XM_011524474 XP_011522776 XM_011546333 XP_011544635 XM_011546334 XP_011544636 XM_011546335 XP_011544637 XM_011546336 XP_011544638 XM_011546337 XP_011544639 XM_011546338 XP_011544640 XM_011546339 XP_011544641 XM_011547464 XP_011545766 XM_011547465 XP_011545767 XM_011547466 XP_011545768 XM_011547467 XP_011545769 XM_011547468 XP_011545770 XM_011547469 XP_011545771 XM_011547470 XP_011545772 XR_429873 XR_429875 XR_429876 XR_430745 XR_430747 XR_430898 XR_430900 XR_430901 XR_934416 XR_934417 XR_934418 XR_951533 XR_952465 XR_952466 XR_952467 NM_001159330 NM_001282290 NP_001269219 NM_174919 NP_777579 NM_199282 NP_954976
|
| Function |
Rho GTPase-activating protein which may be involved in clathrin-mediated endocytosis. GTPase activators for the Rho-type GTPases act by converting them to an inactive GDP-bound state. Has activity toward CDC42 and RAC1 (By similarity). {ECO:0000250}.
|
| Subcellular Location |
Cytoplasm {ECO:0000250}. Membrane {ECO:0000250}; Peripheral membrane protein {ECO:0000250}.
|
| Tissue Specificity |
Expressed in germinal center B-cell, spleen, chronic lymphocytic leukemia, pancreatic cancer and lung cancer. {ECO:0000269|PubMed:15492870}.
|