| Gene Symbol |
INPP5J
|
| Entrez Gene |
27124
|
| Alt Symbol |
INPP5, PIB5PA, PIPP
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
inositol polyphosphate-5-phosphatase J
|
| Other Description |
inositol polyphosphate 5-phosphatase J|phosphatidylinositol (4,5) bisphosphate 5-phosphatase, A|phosphatidylinositol 4,5-bisphosphate 5-phosphatase A
|
| Swissprots |
Q6ZTH6 Q15735 Q8N902 Q32M61 B3KS54 Q9UDT9
|
| Accessions |
AAD15618 EAW59936 EAW59937 EAW59938 EAW59939 EAW59940 Q15735 AK092859 BAG52616 AK095944 BAC04657 AK126610 BAC86611 AK293992 BAG57356 AK308921 AK309548 AW014134 BC041652 BC109288 AAI09289 BU507439 BU584792 U45975 AAB03216 XM_011530143 XP_011528445 NM_014422 NM_001002837 NP_001002837 NM_001284285 NP_001271214 NM_001284286 NP_001271215 NM_001284287 NP_001271216 NM_001284288 NP_001271217 NM_001284289 NP_001271218
|
| Function |
Inositol 5-phosphatase, which converts inositol 1,4,5- trisphosphate to inositol 1,4-bisphosphate. Also converts phosphatidylinositol 4,5-bisphosphate to phosphatidylinositol 4- phosphate and inositol 1,3,4,5-tetrakisphosphate to inositol 1,3,4-trisphosphate in vitro. May be involved in modulation of the function of inositol and phosphatidylinositol polyphosphate- binding proteins that are present at membranes ruffles (By similarity). {ECO:0000250}.
|
| Subcellular Location |
Cytoplasm {ECO:0000250}. Note=Predominantly localized to membrane ruffles. {ECO:0000250}.
|
| Top Pathways |
Inositol phosphate metabolism, Phosphatidylinositol signaling system
|