| Gene Symbol |
PLOD1
|
| Entrez Gene |
5351
|
| Alt Symbol |
EDS6, LH, LH1, LLH, PLOD
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
procollagen-lysine, 2-oxoglutarate 5-dioxygenase 1
|
| Other Description |
lysine hydroxylase|lysyl hydroxlase 1|procollagen-lysine 1, 2-oxoglutarate 5-dioxygenase 1|procollagen-lysine,2-oxoglutarate 5-dioxygenase 1
|
| Swissprots |
Q9H132 Q02809 B4DR87 Q96AV9
|
| Accessions |
AAD52693 AAM12752 EAW71724 EAW71725 Q02809 AK124035 AK294688 BAG57849 AK295254 BAG58243 AK299150 BAG61199 AK312243 BAG35176 AK316285 BAH14656 AU139472 BC016657 AAH16657 BQ447373 DC334246 M98252 XM_011541593 XP_011539895 XM_011541594 XP_011539896 NM_000302 NP_000293
|
| Function |
Forms hydroxylysine residues in -Xaa-Lys-Gly- sequences in collagens. These hydroxylysines serve as sites of attachment for carbohydrate units and are essential for the stability of the intermolecular collagen cross-links.
|
| Subcellular Location |
Rough endoplasmic reticulum membrane; Peripheral membrane protein; Lumenal side.
|
| Top Pathways |
Lysine degradation
|