CRY2

Gene Symbol	CRY2
Entrez Gene	1408
Alt Symbol	HCRY2, PHLL2
Species	Human
Gene Type	protein-coding
Description	cryptochrome circadian clock 2
Other Description	cryptochrome 2 (photolyase-like)|cryptochrome-2|growth-inhibiting protein 37
Swissprots	B4DH32 O75148 B4DZD6 Q49AN0 Q8IV71
Accessions	ABM64210 EAW68029 EAW68030 Q49AN0 AB014558 BAA31633 AI375851 AK001194 AK291260 BAF83949 AK294904 BAG57993 AK295627 BAG58504 AK302865 BAG64048 BC035161 AAH35161 BC041814 AAH41814 BG260501 DC306642 DC330290 EU219622 ACA14134 JF432374 ADZ15591 NM_001127457 NP_001120929 NM_021117 NP_066940
Function	Transcriptional repressor which forms a core component of the circadian clock. The circadian clock, an internal time- keeping system, regulates various physiological processes through the generation of approximately 24 hour circadian rhythms in gene expression, which are translated into rhythms in metabolism and behavior. It is derived from the Latin roots 'circa' (about) and 'diem' (day) and acts as an important regulator of a wide array of physiological functions including metabolism, sleep, body temperature, blood pressure, endocrine, immune, cardiovascular, and renal function. Consists of two major components: the central clock, residing in the suprachiasmatic nucleus (SCN) of the brain, and the peripheral clocks that are present in nearly every tissue and organ system. Both the central and peripheral clocks can be reset by environmental cues, also known as Zeitgebers (German for 'timegivers'). The predominant Zeitgeber for the central clock is light, which is sensed by retina and
Subcellular Location	Cytoplasm {ECO:0000269|PubMed:9801304}. Nucleus {ECO:0000269|PubMed:9801304}. Note=Translocated to the nucleus through interaction with other Clock proteins such as PER2 or ARNTL.
Tissue Specificity	Expressed in all tissues examined including fetal brain, fibroblasts, heart, brain, placenta, lung, liver, skeletal muscle, kidney, pancreas, spleen, thymus, prostate, testis, ovary, small intestine, colon and leukocytes. Highest levels in heart and skeletal muscle. {ECO:0000269|PubMed:8909283, ECO:0000269|PubMed:9801304}.
Top Pathways	Circadian rhythm

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Human CRY2 full length protein - ab152300 from Abcam Category Protein Source Wheat germ Species Human

Human CRY2 protein fragment - ab114947 from Abcam Category Protein Source Wheat germ Species Human

CRY2 Antibody Blocking Peptide - LS-E8090 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

Recombinant Human CRY2 Protein - H00001408-P01 from Novus Biologicals Category Protein Prices $319.00 Sizes 2 µg Source Wheat Germ Species Human

Recombinant Human CRY2 Protein - H00001408-Q01 from Novus Biologicals Category Protein Prices $369.00, $529.00 Sizes 10 µg, 25 µg Source Wheat Germ Species Human

CRY2 Peptide - P1743 from Novus Biologicals Category Peptide Species Human

CRY2-Antibody-N-term-Blocking-Peptide - BP16729a from Abgent, a WuXi AppTec company Category Peptide Prices $80.00 Sizes 100 µg

Cry2-Antibody-C-term-Blocking-Peptide - BP6135a from Abgent, a WuXi AppTec company Category Peptide Prices $80.00 Sizes 100 µg

Bt Cry2Ab protein - 30R-3321 from Fitzgerald Category Protein Prices $475.00 Sizes 10 µg

Cryptochrome 2 Blocking Peptide - 33R-3945 from Fitzgerald Category Peptide Prices $130.00 Sizes 100 µg

Cryptochrome-2 - H00001408-P01 from Acris Antibodies Category Protein Prices $310.00 Sizes 2 µg Species Human

Cryptochrome-2 - H00001408-Q01-10 from Acris Antibodies Category Protein Prices $380.00 Sizes 10 µg Species Human

Cryptochrome-2 - H00001408-Q01-25 from Acris Antibodies Category Protein Prices $500.00 Sizes 25 µg Species Human

CRY2 fusion protein - Ag5085 from Proteintech Group Category Protein Prices $199.00 Sizes 50 μg Source E. coli -derived, PET28a Species Human

Recombinant Human CRY2 - CRY2-26941TH from Creative Biomart Category Protein Source Wheat germ

Recombinant Human CRY2, His-tagged - CRY2-11597H from Creative Biomart Category Protein Source E.coli Species Human

Recombinant Human CRY2, MYC/DDK-tagged - CRY2-1159H from Creative Biomart Category Protein Source HEK293 cells Species Human

Recombinant Human Cryptochrome-2(CRY2) - CSB-YP673229HU CSB-EP673229HU CSB-BP673229HU CSB-MP673229HU from Cusabio Category Protein Source Yeast or E.coli or Baculovirus or Mammalian cell Species Human

Cryptochrome-2 (transcript variant 1) - TP307337 from Acris Antibodies Category Protein Prices $680.00 Sizes 20 µg Source HEK293 cells Species Human

CRY2 Recombinant Protein Antigen - NBP1-86273PEP from Novus Biologicals Category Protein Prices $199.00 Sizes 100 µl Source E.coli Species Human

CRY2 Peptide, Human - M34GP03670H from Creative Peptides Category Peptide Source Synthetic. Species Human

Cryptochrome-2 (CRY2), Recombinant Protein - MBS1313785 from MyBioSource Category Protein Prices $1,395.00, $1,395.00, $1,610.00, $1,610.00, $2,330.00, $2,330.00, $2,770.00, $2,770.00 Sizes 500 µg (E-Coli), 50 µg (Baculovirus), 500 µg (Yeast), 50 µg (Mammalian-Cell), 1 mg (E-Coli), 100 µg (Baculovirus), 1 mg (Yeast), 100 µg (Mammalian-Cell) Source E Coli or Yeast or Baculovirus or Mammalian Cell Species Human

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