| Gene Symbol |
CABP4
|
| Entrez Gene |
57010
|
| Alt Symbol |
CSNB2B
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
calcium binding protein 4
|
| Other Description |
calcium-binding protein 4
|
| Swissprots |
Q8N4Z2 Q8WWY5 P57796
|
| Accessions |
EAW74627 EAW74628 EAW74629 EAW74630 P57796 AK311199 AL712439 AY039217 AAK83462 BC033167 AAH33167 BM665388 XM_005274114 XP_005274171 XM_011545181 XP_011543483 XM_011545182 XP_011543484 XM_011545183 XP_011543485 XM_011545184 XP_011543486 NM_001300895 NP_001287824 NM_001300896 NP_001287825 NM_145200 NP_660201
|
| Function |
Involved in normal synaptic function through regulation of Ca(2+) influx and neurotransmitter release in photoreceptor synaptic terminals and in auditory transmission. Modulator of CACNA1D and CACNA1F, suppressing the calcium-dependent inactivation and shifting the activation range to more hyperpolarized voltages (By similarity). {ECO:0000250}.
|
| Subcellular Location |
Cytoplasm {ECO:0000269|PubMed:19338761}. Note=Found in rod spherules and cone pedicles of the presynapses from both types of photoreceptors. {ECO:0000250}.
|
| Tissue Specificity |
Expressed in retina and in the inner hair cells (IHC) of the cochlea.
|
![Western Blot: CABP4 Overexpression Lysate (Adult Normal) [NBL1-08624] Left-Empty vector transfected control cell lysate (HEK293 cell lysate); Right -Over-expression Lysate for CABP4.](http://www.bioprodhub.com/system/product_images/cel_products/5/sub_2/9010_CABP4%2520Overexpression%2520Lysate%2520(Adult%2520Normal)-Western%2520Blot-NBL1-08624-img0002.jpg)