Gene Symbol | CABP4 |
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Entrez Gene | 57010 |
Alt Symbol | CSNB2B |
Species | Human |
Gene Type | protein-coding |
Description | calcium binding protein 4 |
Other Description | calcium-binding protein 4 |
Swissprots | Q8N4Z2 Q8WWY5 P57796 |
Accessions | EAW74627 EAW74628 EAW74629 EAW74630 P57796 AK311199 AL712439 AY039217 AAK83462 BC033167 AAH33167 BM665388 XM_005274114 XP_005274171 XM_011545181 XP_011543483 XM_011545182 XP_011543484 XM_011545183 XP_011543485 XM_011545184 XP_011543486 NM_001300895 NP_001287824 NM_001300896 NP_001287825 NM_145200 NP_660201 |
Function | Involved in normal synaptic function through regulation of Ca(2+) influx and neurotransmitter release in photoreceptor synaptic terminals and in auditory transmission. Modulator of CACNA1D and CACNA1F, suppressing the calcium-dependent inactivation and shifting the activation range to more hyperpolarized voltages (By similarity). {ECO:0000250}. |
Subcellular Location | Cytoplasm {ECO:0000269|PubMed:19338761}. Note=Found in rod spherules and cone pedicles of the presynapses from both types of photoreceptors. {ECO:0000250}. |
Tissue Specificity | Expressed in retina and in the inner hair cells (IHC) of the cochlea. |
CaBP4 CRISPR/Cas9 KO Plasmid (h) - sc-412748 from Santa Cruz Biotechnology
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CaBP4 HDR Plasmid (h) - sc-412748-HDR from Santa Cruz Biotechnology
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CaBP4 Double Nickase Plasmid (h) - sc-412748-NIC from Santa Cruz Biotechnology
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CaBP4 Double Nickase Plasmid (h2) - sc-412748-NIC-2 from Santa Cruz Biotechnology
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CaBP4 CRISPR Activation Plasmid (h) - sc-412748-ACT from Santa Cruz Biotechnology
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CaBP4 CRISPR Activation Plasmid (h2) - sc-412748-ACT-2 from Santa Cruz Biotechnology
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CaBP4 Lentiviral Activation Particles (h) - sc-412748-LAC from Santa Cruz Biotechnology
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CaBP4 Lentiviral Activation Particles (h2) - sc-412748-LAC-2 from Santa Cruz Biotechnology
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CaBP4 siRNA (h) - sc-105173 from Santa Cruz Biotechnology
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CaBP4 shRNA Plasmid (h) - sc-105173-SH from Santa Cruz Biotechnology
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CaBP4 shRNA (h) Lentiviral Particles - sc-105173-V from Santa Cruz Biotechnology
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MISSION® esiRNA - EHU141111 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN5257 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND5257 from Sigma-Aldrich
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MISSION® 3′UTR Lenti GoClone™ - HUTR04445 from Sigma-Aldrich
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CABP4 siRNA (Human) - CRJ1287 from Cohesion Biosciences
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CABP4 RNAi - H00057010-R01 from Novus Biologicals
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CABP4 - MBS8212197 from MyBioSource
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shRNA set against Human CABP4 (NM_145200.3) - SHH253185 from Creative biogene
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CABP4 shRNA Plasmid (Human) - CHJ1287 from Cohesion Biosciences
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