SPRR1A

Gene Symbol SPRR1A
Entrez Gene 6698
Alt Symbol SPRK
Species Human
Gene Type protein-coding
Description small proline-rich protein 1A
Other Description 19 kDa pancornulin|SPR-IA|cornifin A|cornifin-A|small proline-rich protein IA
Swissprots P35321 Q9UDG4 Q2M303 D3DV31 B1AN47
Accessions AAC26838 AAU88143 EAW53355 EAW53356 EAW53357 P35321 AW204307 BC105081 AAI05082 BC105083 AAI05084 BC111839 AAI11840 BC143782 AAI43783 S73288 NM_001199828 NP_001186757 NM_005987 NP_005978
Function Cross-linked envelope protein of keratinocytes. It is a keratinocyte protein that first appears in the cell cytosol, but ultimately becomes cross-linked to membrane proteins by transglutaminase. All that results in the formation of an insoluble envelope beneath the plasma membrane.
Subcellular Location Cytoplasm.

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