Gene Symbol | SPRR1A |
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Entrez Gene | 6698 |
Alt Symbol | SPRK |
Species | Human |
Gene Type | protein-coding |
Description | small proline-rich protein 1A |
Other Description | 19 kDa pancornulin|SPR-IA|cornifin A|cornifin-A|small proline-rich protein IA |
Swissprots | P35321 Q9UDG4 Q2M303 D3DV31 B1AN47 |
Accessions | AAC26838 AAU88143 EAW53355 EAW53356 EAW53357 P35321 AW204307 BC105081 AAI05082 BC105083 AAI05084 BC111839 AAI11840 BC143782 AAI43783 S73288 NM_001199828 NP_001186757 NM_005987 NP_005978 |
Function | Cross-linked envelope protein of keratinocytes. It is a keratinocyte protein that first appears in the cell cytosol, but ultimately becomes cross-linked to membrane proteins by transglutaminase. All that results in the formation of an insoluble envelope beneath the plasma membrane. |
Subcellular Location | Cytoplasm. |
SPRR1A CRISPR/Cas9 KO Plasmid (h) - sc-416397 from Santa Cruz Biotechnology
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SPRR1A HDR Plasmid (h) - sc-416397-HDR from Santa Cruz Biotechnology
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SPRR1A Double Nickase Plasmid (h) - sc-416397-NIC from Santa Cruz Biotechnology
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SPRR1A Double Nickase Plasmid (h2) - sc-416397-NIC-2 from Santa Cruz Biotechnology
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SPRR1A CRISPR Activation Plasmid (h) - sc-416397-ACT from Santa Cruz Biotechnology
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SPRR1A CRISPR Activation Plasmid (h2) - sc-416397-ACT-2 from Santa Cruz Biotechnology
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SPRR1A Lentiviral Activation Particles (h) - sc-416397-LAC from Santa Cruz Biotechnology
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SPRR1A Lentiviral Activation Particles (h2) - sc-416397-LAC-2 from Santa Cruz Biotechnology
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SPRR1A siRNA (h) - sc-78653 from Santa Cruz Biotechnology
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SPRR1A shRNA Plasmid (h) - sc-78653-SH from Santa Cruz Biotechnology
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SPRR1A shRNA (h) Lentiviral Particles - sc-78653-V from Santa Cruz Biotechnology
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MISSION® esiRNA - EHU108781 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN20518 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND20518 from Sigma-Aldrich
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MISSION® 3′UTR Lenti GoClone™ - HUTR02130 from Sigma-Aldrich
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SPRR1A siRNA (Human) - CRH4568 from Cohesion Biosciences
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SPRR1A - MBS8221081 from MyBioSource
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shRNA set against Human Sprr1a (NM_005987.3) - SHH417228 from Creative biogene
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Human SPRR1A siRNA - orb265070 from Biorbyt
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SPRR1A shRNA Plasmid (Human) - CHH4568 from Cohesion Biosciences
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SPRR1A miRNA 3'UTR clone - MiUTR4H-TG12517 from Creative biogene
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