| Gene Symbol |
SEC61A2
|
| Entrez Gene |
55176
|
| Alt Symbol |
-
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
Sec61 alpha 2 subunit (S. cerevisiae)
|
| Other Description |
Sec61 alpha form 2|protein transport protein Sec61 subunit alpha|protein transport protein Sec61 subunit alpha isoform 2|sec61 alpha-2
|
| Swissprots |
F8W773 B4DX72 A8K8D0 Q9H9S3
|
| Accessions |
EAW86323 EAW86324 EAW86325 EAW86326 Q9H9S3 AF346603 AAK29084 AK001440 BAA91692 AK022027 BAB13955 AK022640 BAB14148 AK057532 BAG51930 AK292295 BAF84984 AK301841 BAG63284 BC026179 AAH26179 BP212860 BX645143 JF432518 ADZ15735 NM_001142627 NP_001136099 NM_001142628 NP_001136100 NM_018144 NP_060614 NR_024576 NR_024577
|
| Function |
Appears to play a crucial role in the insertion of secretory and membrane polypeptides into the ER. It is required for assembly of membrane and secretory proteins. Found to be tightly associated with membrane-bound ribosomes, either directly or through adaptor proteins (By similarity). {ECO:0000250}.
|
| Subcellular Location |
Endoplasmic reticulum membrane {ECO:0000250}; Multi-pass membrane protein {ECO:0000250}.
|
| Top Pathways |
Protein export, Vibrio cholerae infection, Phagosome, Protein processing in endoplasmic reticulum
|