FGG

Gene Symbol	FGG
Entrez Gene	2266
Alt Symbol	-
Species	Human
Gene Type	protein-coding
Description	fibrinogen gamma chain
Other Description	fibrinogen, gamma polypeptide
Swissprots	Q9UC62 Q96A14 Q9UC63 Q9UCF3 A8K057 Q53Y18 P02679 P04470 P04469 Q96KJ3
Accessions	AAA52430 AAA52431 AAB59530 AAB59531 AAK19751 AAK19752 CDL78904 EAX04905 EAX04906 EAX04907 EAX04908 EAX04909 EAX04910 EAX04911 EAX04912 EAX04913 EAX04914 EAX04915 EAX04916 EAX04917 EAX04918 EAX04919 EAX04920 EAX04921 EAX04922 EAX04923 P02679 AA936960 AI808530 AK289422 BAF82111 AK290824 BAF83513 AL531173 BC007044 AAH07044 BC021674 AAH21674 BG567044 BT007081 AAP35744 BX538098 CAD98014 X00086 CAA24944 X51473 CAA35837 NM_000509 NP_000500 NM_021870 NP_068656
Function	Together with fibrinogen alpha (FGA) and fibrinogen beta (FGB), polymerizes to form an insoluble fibrin matrix. Has a major function in hemostasis as one of the primary components of blood clots. In addition, functions during the early stages of wound repair to stabilize the lesion and guide cell migration during re- epithelialization. Was originally thought to be essential for platelet aggregation, based on in vitro studies using anticoagulated blood. However, subsequent studies have shown that it is not absolutely required for thrombus formation in vivo. Enhances expression of SELP in activated platelets via an ITGB3- dependent pathway. Maternal fibrinogen is essential for successful pregnancy. Fibrin deposition is also associated with infection, where it protects against IFNG-mediated hemorrhage. May also facilitate the antibacterial immune response via both innate and T-cell mediated pathways. {ECO:0000250|UniProtKB:E9PV24}.
Subcellular Location	Secreted.
Top Pathways	Complement and coagulation cascades, Staphylococcus aureus infection

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Human FGG / Fibrinogen Gamma ELISA Kit (Sandwich ELISA) - LS-F7036 from LifeSpan Bioscience Category ELISA Kit Prices $720.00 Sizes 1 plate Sensitivity 2.52 ng/ml Range 6.25-400 ng/ml

Rat FGG / Fibrinogen Gamma ELISA Kit (Sandwich ELISA) - LS-F8052 from LifeSpan Bioscience Category ELISA Kit Prices $780.00 Sizes 1 plate Sensitivity 2.7 ng/ml Range 6.25-400 ng/ml

Human FGG / Fibrinogen Gamma ELISA Kit (Sandwich ELISA) - LS-F11471 from LifeSpan Bioscience Category ELISA Kit Prices $600.00 Sizes 1 plate Sensitivity 1.56 Range 6.25-400 ng/ml

Fibrinogen Gamma chain, FGy, Human, ELISA Kit - E-EL-H0387 from ARP American Research Products Category ELISA Kit Prices $522.00 Sizes 96 t Sensitivity 9.375 Range 15.625-1000ng/mL

Fibrinogen Gamma (FGg), Human, ELISA Kit - SEC477Hu from ARP American Research Products Category ELISA Kit Prices $720.00 Sizes 96 t Sensitivity 2.65ng/mL Range 6.25-400ng/mL

Fibrinogen Gamma Chain (FGG), Human, ELISA Kit - CSB-E13319h from ARP American Research Products Category ELISA Kit Prices $550.00, $790.00, $791.00, $794.00 Sizes 48 t, 96 t, 5 x 96t, 10 x 96t Sensitivity 25 ng/ml Range 50 ng/ml-2500ng/ml

Fibrinogen gamma chain, FGG, Human, ELISA Kit - E0067h from ARP American Research Products Category ELISA Kit Prices $636.00 Sizes 96 t Range 1.56-100 ng/mL

fibrinogen gamma chain, ELISA Kit - MBS700557 from MyBioSource Category ELISA Kit Prices $250.00, $550.00, $795.00, $2,890.00, $5,465.00 Sizes 24 -strip-wells (Limit 1), 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells Sensitivity The minimum detectable dose of human FGG is typically less than 31.25 ng/ml. The sensitivity of this assay, or Lower Limit of Detection (LLD) was defined as the lowest protein concentration that could be differentiated from zero. It was determined the mean O.D value of 20 replicates of the zero standard added by their three standard deviations. Range 125 ng/ml -8000 ng/ml.

ELISA Kit for Fibrinogen Gamma (FGg) - SEC477Hu from Uscn Life Science Inc. Category ELISA Kit Sensitivity The minimum detectable dose of this kit is typically less than 2.59ng/mL. Range 6.25-400ng/mL The standard curve concentrations used for the ELISA’s were 400ng/mL, 200ng/mL, 100ng/mL, 50ng/mL, 25ng/mL, 12.5ng/mL, 6.25ng/mL

ELISA Kit for Fibrinogen Gamma (FGg) - SEC477Ra from Uscn Life Science Inc. Category ELISA Kit Sensitivity The minimum detectable dose of this kit is typically less than 2.7ng/mL. Range 7.81-500ng/mL The standard curve concentrations used for the ELISA’s were 500ng/mL, 250ng/mL, 125ng/mL, 62.5ng/mL, 31.25ng/mL, 15.63ng/mL, 7.81ng/mL

Human Fibrinogen Gamma Chain (FGG)ELISA Kit - CSB-E13319h from Cusabio Category ELISA Kit Sensitivity 31.25 ng/ml Range 125 ng/ml-8000 ng/ml

Dog FGG / Fibrinogen Gamma ELISA Kit (Sandwich ELISA) - LS-F13670 from LifeSpan Bioscience Category ELISA Kit Prices $700.00 Sizes 1 plate Sensitivity 7.8 ng/ml Range 6.25-400 ng/ml

Bovine FGG / Fibrinogen Gamma ELISA Kit (Custom ELISA) - LS-F13672 from LifeSpan Bioscience Category ELISA Kit Prices $700.00 Sizes 1 plate Sensitivity To be determined Range 6.25-400 ng/ml

Mouse FGG / Fibrinogen Gamma ELISA Kit (Sandwich ELISA) - LS-F13673 from LifeSpan Bioscience Category ELISA Kit Prices $530.00 Sizes 1 plate Sensitivity 3.12 Range 6.25-400 ng/ml

Rat FGG / Fibrinogen Gamma ELISA Kit (Custom ELISA) - LS-F13671 from LifeSpan Bioscience Category ELISA Kit Prices $530.00 Sizes 1 plate Sensitivity To be determined Range 6.25-400 ng/ml

Human FGGamma(Fibrinogen Gamma chain) ELISA Kit - E-EL-H0387 from Iwai North America Inc. Category ELISA Kit Prices $580.00 Sizes 1 kit Sensitivity 9.38 ng/mLng/mL Range 15.63~1000 ng/mL

Human ACHAP (Acetylcholinesterase Associated Protein) CLIA Kit - E-CL-H0281 from Iwai North America Inc. Category CLIA Kit Prices $722.50 Sizes 1 kit Sensitivity 0.094ng/mL Range 0.156-10ng/mL

Human Fibrinogen Gamma chain ELISA Kit - abx252464 from Abbexa Category ELISA Kit Sensitivity 9.375 ng/ml Range 15.625 ng/ml - 1000 ng/ml

Human Fibrinogen gamma chain ELISA Kit - abx253654 from Abbexa Category ELISA Kit Range 1.56 ng/ml - 100 ng/ml

Fibrinogen Gamma (FGg), Human, ELISA Kit - DL-FGg-Hu from ARP American Research Products Category ELISA Kit Prices $655.00 Sizes 96 t Range 15.6-1,000 ng/mL

FGgamma (Fibrinogen Gamma chain), CLIA Kit - MBS2530536 from MyBioSource Category CLIA Kit Prices $450.00, $535.00, $2,255.00, $3,975.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells Sensitivity 1.875ng/mL Range 3.125-200ng/mL

Human FGg ELISA Kit - abx575893 from Abbexa Category ELISA Kit Sensitivity 2.65 ng/ml Range 6.25 ng/ml - 400 ng/ml

Human Fibrinogen Gamma Chain (FGG) ELISA Kit - EKC33683 from Biomatik Category ELISA Kit Prices $795.00, $3,021.00, $5,645.00 Sizes 96 t, 5x96t, 10x96t Sensitivity 31.25 ng/ml Range 125 ng/ml-8000 ng/ml

Human Fibrinogen gamma chain ELISA Kit - EKE54248 from Biomatik Category ELISA Kit Prices $731.40, $3,108.45, $5,851.20 Sizes 96 t, 5x96t, 10x96t Sensitivity The minimum detectable dose of this kit is typically less than 0.78 ng/mL Range 1.56-100 ng/mL

FGG - EKH1386 from Nordic BioSite Sensitivity 9.375ng/ml Range 15.625-1000ng/ml

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