FGG

Gene Symbol	FGG
Entrez Gene	2266
Alt Symbol	-
Species	Human
Gene Type	protein-coding
Description	fibrinogen gamma chain
Other Description	fibrinogen, gamma polypeptide
Swissprots	Q9UC62 Q96A14 Q9UC63 Q9UCF3 A8K057 Q53Y18 P02679 P04470 P04469 Q96KJ3
Accessions	AAA52430 AAA52431 AAB59530 AAB59531 AAK19751 AAK19752 CDL78904 EAX04905 EAX04906 EAX04907 EAX04908 EAX04909 EAX04910 EAX04911 EAX04912 EAX04913 EAX04914 EAX04915 EAX04916 EAX04917 EAX04918 EAX04919 EAX04920 EAX04921 EAX04922 EAX04923 P02679 AA936960 AI808530 AK289422 BAF82111 AK290824 BAF83513 AL531173 BC007044 AAH07044 BC021674 AAH21674 BG567044 BT007081 AAP35744 BX538098 CAD98014 X00086 CAA24944 X51473 CAA35837 NM_000509 NP_000500 NM_021870 NP_068656
Function	Together with fibrinogen alpha (FGA) and fibrinogen beta (FGB), polymerizes to form an insoluble fibrin matrix. Has a major function in hemostasis as one of the primary components of blood clots. In addition, functions during the early stages of wound repair to stabilize the lesion and guide cell migration during re- epithelialization. Was originally thought to be essential for platelet aggregation, based on in vitro studies using anticoagulated blood. However, subsequent studies have shown that it is not absolutely required for thrombus formation in vivo. Enhances expression of SELP in activated platelets via an ITGB3- dependent pathway. Maternal fibrinogen is essential for successful pregnancy. Fibrin deposition is also associated with infection, where it protects against IFNG-mediated hemorrhage. May also facilitate the antibacterial immune response via both innate and T-cell mediated pathways. {ECO:0000250|UniProtKB:E9PV24}.
Subcellular Location	Secreted.
Top Pathways	Complement and coagulation cascades, Staphylococcus aureus infection

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Human Fibrinogen gamma chain full length protein - ab202200 from Abcam Category Protein Source E. coli Species Human

Human Fibrinogen gamma chain protein fragment - ab158441 from Abcam Category Protein Source Wheat germ Species Human

FGG / Fibrinogen Gamma Antibody Blocking Peptide - LS-E16274 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

FGG / Fibrinogen Gamma Antibody Blocking Peptide - LS-E16273 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

FGG / Fibrinogen Gamma Antibody Blocking Peptide - LS-E8309 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

FGG / Fibrinogen Gamma Antibody Blocking Peptide - LS-E8864 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

FGG / Fibrinogen Gamma Antibody Blocking Peptide - LS-E8863 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

Fibrinogen gamma chain Partial Recombinant Protein - H00002266-Q01 from Novus Biologicals Category Protein Prices $369.00 Sizes 10 µg Species Human

FIBG-Antibody-C-term-Blocking-Peptide - BP6583b from Abgent, a WuXi AppTec company Category Peptide Prices $80.00 Sizes 100 µg

FGG-Antibody-C-term-Blocking-Peptide - BP7325b from Abgent, a WuXi AppTec company Category Peptide Prices $80.00 Sizes 100 µg

FGG-Antibody-N-term-Blocking-Peptide - BP7325a from Abgent, a WuXi AppTec company Category Peptide Prices $80.00 Sizes 100 µg

NATIVE Human FIBRIN DEGRADATION PRODUCT E Protein (OPSA10509) - OPSA10509 from Aviva Systems Biology Category Protein Prices $375.00 Sizes 100 µg Species Human

NATIVE Human FIBRIN DEGRADATION PRODUCT X Protein (OPSA10510) - OPSA10510 from Aviva Systems Biology Category Protein Prices $530.00 Sizes 200 µg Species Human

NATIVE Human FIBRIN DEGRADATION PRODUCT Y Protein (OPSA10511) - OPSA10511 from Aviva Systems Biology Category Protein Prices $510.00 Sizes 200 µg Species Human

Human FGG R protein - orb163393 from Biorbyt Category Protein Prices $306.00, $451.00, $1,751.00, $2,474.00 Sizes 10 μg, 50 μg, 500 μg, 1 mg Source Human Cells Species Human

FGG Blocking Peptide - 33R-8054 from Fitzgerald Category Peptide Prices $130.00 Sizes 100 µg

FGG Blocking Peptide - 33R-3672 from Fitzgerald Category Peptide Prices $130.00 Sizes 100 µg

FGG protein (His tag) - 80R-4087 from Fitzgerald Category Protein Prices $275.00 Sizes 20 µg Source E.coli

Human Fibrinogen Gamma Protein - abx066577 from Abbexa Category Protein Source E.coli Species Human

Fibrinogen gamma chain (27-437, His-tag) - AR51773PU-N from Acris Antibodies Category Protein Prices $790.00 Sizes 100 µg Source E. coli Species Human

Fibrinogen gamma chain (27-437, His-tag) - AR51773PU-S from Acris Antibodies Category Protein Prices $340.00 Sizes 20 µg Source E. coli Species Human

Fibrinogen gamma chain - H00002266-Q01-10 from Acris Antibodies Category Protein Prices $380.00 Sizes 10 µg Source in vitro transl. Species Human

Fibrinogen gamma chain - H00002266-Q01-25 from Acris Antibodies Category Protein Prices $500.00 Sizes 25 µg Source in vitro transl. Species Human

Fibrinogen Gamma (FGg), Human - 20-8499 from ARP American Research Products Category Protein Prices $349.00 Sizes 50 µg Source E.coli Species Human

FGG fusion protein - Ag8817 from Proteintech Group Category Protein Prices $199.00 Sizes 50 μg Source E. coli -derived, PET28a Species Human

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